Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LHCGR | P22888 | 1/20 | 0.58 |
| ▸ | HHAT | Q5VTY9 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8163727 | 0.89 | LHCGR (0.66) | LHCGRMAPK1NPSR1 | |
| SCHEMBL7880458 | 0.89 | LHCGR (0.54) | LHCGRHHATPOLB | |
| SCHEMBL7885774 | 0.89 | LHCGR (0.55) | LHCGRHHATPOLBMAPK1NPSR1 | |
| SCHEMBL7888305 | 0.89 | LHCGR (0.55) | LHCGRHHATPOLBMAPK1NPSR1 | |
| SCHEMBL7880417 | 0.89 | POLB (0.63) | LHCGRPOLB | |
| SCHEMBL7880530 | 0.89 | POLB (0.63) | LHCGRPOLB | |
| SCHEMBL7880305 | 0.89 | LHCGR (0.58) | LHCGRHHATPOLB | |
| SCHEMBL7889881 | 0.88 | LHCGR (0.56) | LHCGRHHATPOLBMAPK1NPSR1 | |
| SCHEMBL7888235 | 0.87 | LHCGR (0.55) | LHCGRHHATMAPK1NPSR1 | |
| SCHEMBL7889959 | 0.87 | LHCGR (0.55) | LHCGRHHATPOLBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6177443-B1 | ANTIDIABETIC AGENTS | NOVO NORDISK A/S (DK) | 2001-01-23 | — | — | US | claimed |
| US-6177443-B1 | ANTIDIABETIC AGENTS | NOVO NORDISK A/S (DK) | 2001-01-23 | — | — | US | disclosed |
| EP-0973778-A1 | 4,5,6,7-TETRAHYDRO-THIENO 3,2-c]PYRIDINE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2000-01-26 | — | — | EP | disclosed |
| WO-1998040385-A1 | 4,5,6,7-TETRAHYDRO-THIENO[3,2-c]PYRIDINE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1998-09-17 | — | — | WO | disclosed |