Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HHAT | Q5VTY9 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | LHCGR | P22888 | 5/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7889847 | 0.89 | NPSR1 (0.55) | HHATNPSR1L3MBTL1POLBLHCGR | |
| SCHEMBL7887385 | 0.88 | POLB (0.63) | NPSR1L3MBTL1POLBLHCGR | |
| SCHEMBL7887769 | 0.88 | POLB (0.52) | HHATNPSR1L3MBTL1POLBLHCGR | |
| SCHEMBL7889959 | 0.88 | LHCGR (0.55) | HHATNPSR1L3MBTL1POLBLHCGR | |
| SCHEMBL7880264 | 0.88 | LHCGR (0.60) | NPSR1L3MBTL1POLBLHCGR | |
| SCHEMBL7887505 | 0.86 | POLB (0.53) | HHATNPSR1L3MBTL1POLBLHCGR | |
| SCHEMBL7880247 | 0.86 | NPSR1 (0.49) | HHATNPSR1L3MBTL1POLBLHCGR | |
| SCHEMBL7880476 | 0.86 | NPSR1 (0.50) | HHATNPSR1L3MBTL1POLBLHCGR | |
| SCHEMBL7885929 | 0.86 | POLB (0.50) | HHATNPSR1L3MBTL1POLBLHCGR | |
| SCHEMBL7887450 | 0.86 | POLB (0.50) | HHATNPSR1L3MBTL1POLBLHCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6177443-B1 | ANTIDIABETIC AGENTS | NOVO NORDISK A/S (DK) | 2001-01-23 | — | — | US | disclosed |
| EP-0973778-A1 | 4,5,6,7-TETRAHYDRO-THIENO 3,2-c]PYRIDINE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2000-01-26 | — | — | EP | disclosed |
| WO-1998040385-A1 | 4,5,6,7-TETRAHYDRO-THIENO[3,2-c]PYRIDINE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1998-09-17 | — | — | WO | disclosed |