Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 12/20 | 0.56 |
| ▸ | RXRB | P28702 | 8/20 | 0.56 |
| ▸ | RXRG | P48443 | 6/20 | 0.56 |
| ▸ | RARB | P10826 | 11/20 | 0.52 |
| ▸ | RARG | P13631 | 11/20 | 0.52 |
| ▸ | RARA | P10276 | 8/20 | 0.52 |
| ▸ | CYP26A1 | O43174 | 6/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.51 |
| ▸ | CYP26B1 | Q9NR63 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | GMNN | O75496 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7880475 | 0.82 | CYP3A4 (0.40) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL7872167 | 0.81 | RARB (0.61) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL7878338 | 0.80 | RXRA (0.49) | RXRARXRBRXRGRARBRARG | |
| Hydrochloric Acid SCHEMBL7878396 | 0.79 | RXRA (0.48) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL7878388 | 0.77 | RXRA (0.48) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL9165893 | 0.76 | RXRA (0.69) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL5084209 | 0.74 | RXRA (0.66) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL8973028 | 0.74 | RXRA (0.61) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL9175151 | 0.73 | RXRA (0.74) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL7720657 | 0.73 | RXRA (1.00) | RXRARXRBRXRGRARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326510-B1 | SKIN DISORDERS; ANTICANCER AGENTS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (FR) | 2001-12-04 | — | — | US | claimed |
| US-6326510-B1 | SKIN DISORDERS; ANTICANCER AGENTS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (FR) | 2001-12-04 | — | — | US | disclosed |
| EP-0901462-A1 | BI-AROMATIC COMPOUNDS, COMPOSITIONS CONTAINING THEM AND USES | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA, ( CIRD GALDERMA) (FR) | 1999-03-17 | — | — | EP | disclosed |
| WO-1998034909-A1 | BI-AROMATIC COMPOUNDS, COMPOSITIONS CONTAINING THEM AND USES | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (C.I.R.D. GALDERMA) (FR) | 1998-08-13 | — | — | WO | disclosed |