⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11202647 | 0.98 | ALAD (0.58) | — | |
| SCHEMBL31000806 | 0.83 | CES2 (0.56) | — | |
| SCHEMBL7040071 | 0.82 | CES2 (0.45) | — | |
| SCHEMBL1771045 | 0.81 | — | — | |
| SCHEMBL24579379 | 0.80 | ALAD (0.39) | — | |
| SCHEMBL1665488 | 0.79 | — | — | |
| SCHEMBL545198 | 0.79 | — | — | |
| SCHEMBL19638255 | 0.79 | CTPS1 (0.49) | — | |
| SCHEMBL27251712 | 0.76 | ALAD (0.38) | — | |
| SCHEMBL2652069 | 0.76 | ALAD (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 126 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111020804-B | Processing method of moisture-absorbing heating type blended fabric | 吉祥三宝高科纺织有限公司 | 2021-06-15 | — | — | CN | claimed |
| CN-109369611-B | Synthetic method of 4-chlorothiophene-2-carbonyl derivative | 上海毕得医药科技有限公司 | 2020-11-10 | — | — | CN | claimed |
| CN-111020804-A | Processing method of moisture-absorbing heating type blended fabric | 吉祥三宝高科纺织有限公司 | 2020-04-17 | — | — | CN | claimed |
| CN-109369611-A | A kind of synthetic method of 4- chlorothiophene -2- carbonyl derivative | 上海毕得医药科技有限公司 | 2019-02-22 | — | — | CN | claimed |
| EP-2616466-A2 | PROCESS FOR DETERMINING THE SUITABILITY FOR DISTRIBUTION OF A BATCH OF A THIOPHENE-2-CARBOXAMIDE DERIVATIVE | Medichem, S.A. (ES) | 2013-07-24 | — | — | EP | claimed |
| WO-2012035057-A2 | PROCESS FOR DETERMINING THE SUITABILITY FOR DISTRIBUTION OF A BATCH OF A THIOPHENE-2-CARBOXAMIDE DERIVATIVE | MEDICHEM S.A. (ES) | 2012-03-22 | — | — | WO | claimed |
| CN-1158851-A | Process of preparing 4-chlor-2-thiophenecar-boxylic acid | PFIZER (US) | 1997-09-10 | — | — | CN | claimed |
| US-5648502-A | Regioselective synthesis of 4-chloro-2-thiophenecarboxylic acid | PFIZER INC. (US) | 1997-07-15 | — | — | US | claimed |
| EP-0669924-B1 | REGIOSELECTIVE SYNTHESIS OF 4-CHLORO-2-THIOPHENECARBOXYLIC ACID | PFIZER (US) | 1996-12-11 | — | — | EP | claimed |
| EP-0669924-A1 | REGIOSELECTIVE SYNTHESIS OF 4-CHLORO-2-THIOPHENECARBOXYLIC ACID. | PFIZER (US) | 1995-09-06 | — | — | EP | claimed |
| CN-1093704-A | Regioselective synthesis of 4-chloro-2-thiophenecarboxylic acid | PFIZER (US) | 1994-10-19 | — | — | CN | claimed |
| WO-1994012505-A1 | REGIOSELECTIVE SYNTHESIS OF 4-CHLORO-2-THIOPHENECARBOXYLIC ACID | PFIZER INC. (US) | 1994-06-09 | — | — | WO | claimed |
| JP-10081683-A | — | — | None | — | — | JP | disclosed |
| EP-4667054-A2 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | Novartis AG (CH) | 2025-12-24 | — | — | EP | disclosed |
| EP-3880660-B1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS AG (CH) | 2025-07-02 | — | — | EP | disclosed |
| CN-113166065-B | Compounds and compositions for treating disorders associated with NLRP activity | 诺华股份有限公司 | 2025-04-15 | — | — | CN | disclosed |
| US-4087539-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIPYRETICS, SMOOTH MUSCLE RELAXANTS | SYNTEX (U.S.A.) INC. (US) | 1978-05-02 | — | — | US | disclosed |
| US-4086241-A | Benzothiazolylimidazolidinone esters of furyl and thienyl substituted acids | VELSICOL CHEMICAL CORPORATION (US) | 1978-04-25 | — | — | US | disclosed |
| US-4061648-A | HERBICIDES | VELSICOL CHEMICAL CORPORATION (US) | 1977-12-06 | — | — | US | disclosed |
| US-4032647-A | HYPOLIPIDEMIC AGENTS | RICHARDSON-MERRELL INC. (US) | 1977-06-28 | — | — | US | disclosed |