SCHEMBL7882155

SCHEMBL7882155

NC1(C2(N)C=Cc3ccccc3C2)C=Cc2ccccc2C1

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 1/20 0.36
CA1 P00915 2/20 0.36
CA2 P00918 2/20 0.36
IDO1 P14902 2/20 0.31
MAOB P27338 1/20 0.31
GAA P10253 1/20 0.30
MAPT P10636 1/20 0.30
HTR2C P28335 1/20 0.30
HTR2B P41595 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1725344 0.83 PARP1 (0.36) PARP1CA1CA2IDO1MAOB
SCHEMBL8351271 0.79 PARP1 (0.34) PARP1CA1CA2
SCHEMBL2288761 0.77 PARP1 (0.39) PARP1CA1CA2MAOBGAA
SCHEMBL11856621 0.76 MAOA (0.36) PARP1CA1CA2MAOB
SCHEMBL28699182 0.75 NPSR1 (0.36) PARP1CA1CA2MAOBGAA
SCHEMBL11038027 0.75 CA1 (0.32) PARP1CA1CA2
SCHEMBL31520302 0.74 PARP1 (0.36) PARP1CA1CA2MAOBGAA
SCHEMBL29791692 0.74 PARP1 (0.36) PARP1CA1CA2MAOBGAA
SCHEMBL1697644 0.74 PARP1 (0.36) PARP1CA1CA2MAOBGAA
SCHEMBL258234 0.74 PARP1 (0.36) PARP1CA1CA2MAOBGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6270640-B1 SEPARATING A MIXTURE OF TWO ENENTIOMERS WHERE DIFFERENT AFFINITIES CAUSE THEM TO MOVE THROUGH THE POLYMERIZED DIPEPTIDE CHIRAL MICELLE AT DIFFERENT VELOCITIES BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE 2001-08-07 US disclosed