Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 17/20 | 0.66 |
| ▸ | CASP7 | P55210 | 11/20 | 0.66 |
| ▸ | CASP1 | P29466 | 7/20 | 0.66 |
| ▸ | CASP4 | P49662 | 3/20 | 0.66 |
| ▸ | CASP9 | P55211 | 5/20 | 0.59 |
| ▸ | CASP10 | Q92851 | 3/20 | 0.59 |
| ▸ | CASP8 | Q14790 | 2/20 | 0.59 |
| ▸ | CASP5 | P51878 | 1/20 | 0.48 |
| ▸ | CASP6 | P55212 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7886082 | 0.93 | CASP3 (0.59) | CASP3CASP7CASP1CASP4CASP9 | |
| SCHEMBL7878192 | 0.88 | CASP3 (0.68) | CASP3CASP7CASP1CASP4CASP9 | |
| SCHEMBL9962253 | 0.88 | CASP3 (0.83) | CASP3CASP7CASP1CASP4CASP9 | |
| SCHEMBL7888193 | 0.87 | CASP3 (0.60) | CASP3CASP7CASP1CASP4CASP9 | |
| SCHEMBL9962188 | 0.86 | CASP3 (0.88) | CASP3CASP7CASP1CASP4CASP9 | |
| SCHEMBL9962013 | 0.85 | CASP3 (0.88) | CASP3CASP7CASP1CASP4CASP9 | |
| SCHEMBL7889716 | 0.84 | CASP3 (0.65) | CASP3CASP7CASP1CASP4CASP9 | |
| SCHEMBL9962318 | 0.83 | CASP3 (0.73) | CASP3CASP7CASP1CASP4CASP9 | |
| SCHEMBL9962293 | 0.82 | CASP3 (0.72) | CASP3CASP7CASP1CASP4CASP9 | |
| SCHEMBL9962260 | 0.82 | CASP3 (0.83) | CASP3CASP7CASP1CASP4CASP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010133000-A1 | SELECTIVE CASPASE INHIBITORS AND USES THEREOF | NEW WORLD LABORATORIES INC. (CA) | 2010-11-25 | — | — | WO | disclosed |