Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.44 |
| ▸ | HTR2C | P28335 | 3/20 | 0.44 |
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | HTR1D | P28221 | 2/20 | 0.44 |
| ▸ | HTR2B | P41595 | 2/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 8/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | EED | O75530 | 4/20 | 0.37 |
| ▸ | SUZ12 | Q15022 | 4/20 | 0.37 |
| ▸ | EZH2 | Q15910 | 4/20 | 0.37 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6948960 | 0.90 | MTNR1A (0.40) | HTR2AHTR2CHTR1AHTR1DHTR2B | |
| Hydrochloric Acid SCHEMBL6948695 | 0.88 | MTNR1A (0.39) | HTR2AHTR2CHTR1AHTR1DHTR2B | |
| SCHEMBL17841440 | 0.85 | MTNR1B (0.43) | MTNR1AMTNR1BP2RX7EEDSUZ12 | |
| SCHEMBL293436 | 0.82 | MTNR1B (0.41) | MTNR1AMTNR1BP2RX7EEDSUZ12 | |
| SCHEMBL583214 | 0.82 | MTNR1B (0.41) | MTNR1AMTNR1BP2RX7EEDSUZ12 | |
| SCHEMBL6950092 | 0.82 | MTNR1A (0.44) | MTNR1AMTNR1BP2RX7EEDSUZ12 | |
| SCHEMBL14405818 | 0.82 | MTNR1B (0.50) | MTNR1AMTNR1BP2RX7EEDSUZ12 | |
| SCHEMBL6950651 | 0.80 | HTR2C (0.47) | HTR2AHTR2CHTR1AHTR1DHTR2B | |
| SCHEMBL31561748 | 0.79 | MTNR1A (0.42) | MTNR1AMTNR1BP2RX7EEDSUZ12 | |
| SCHEMBL294333 | 0.79 | MTNR1A (0.40) | MTNR1AMTNR1BP2RX7EEDSUZ12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0819000-A4 | NODULISPORIC ACID DERIVATIVES | MERCK & CO INC (US) | 2001-04-11 | — | — | EP | disclosed |
| EP-0819000-A1 | NODULISPORIC ACID DERIVATIVES | Merck & Co., Inc. (US) | 1998-01-21 | — | — | EP | disclosed |