Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRA | P11474 | 5/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | FBP1 | P09467 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KLF5 | Q13887 | 2/20 | 0.32 |
| ▸ | RHEB | Q15382 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7880004 | 0.99 | ESRRA (0.36) | ESRRACYP1A2CYP3A4CYP2C19LMNA | |
| SCHEMBL7881844 | 0.88 | RHEB (0.44) | ESRRAKDM4EHPGDFBP1RHEB | |
| SCHEMBL7879460 | 0.87 | CYP3A4 (0.37) | ESRRACYP3A4CYP2C19BRD4 | |
| SCHEMBL7884381 | 0.86 | SLC9A1 (0.33) | CYP1A2CYP3A4CYP2C19MAPTKDM4E | |
| SCHEMBL7879818 | 0.85 | LMNA (0.46) | LMNAMAPTHPGDFBP1MEN1 | |
| SCHEMBL7877527 | 0.85 | SLC9A1 (0.39) | NPC1RAB9AMEN1KMT2AKLF5 | |
| Hydrochloric Acid SCHEMBL7878278 | 0.85 | SLC9A1 (0.32) | CYP1A2CYP3A4CYP2C19KDM4EHPGD | |
| Hydrochloric Acid SCHEMBL7873614 | 0.85 | LMNA (0.46) | LMNAMAPTHPGDFBP1MEN1 | |
| SCHEMBL7877943 | 0.85 | SLC6A4 (0.44) | — | |
| SCHEMBL7873269 | 0.84 | ESRRA (0.38) | ESRRAKDM4EHPGDFBP1RHEB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248772-B1 | HYPOTENSIVE AGENTS; ANTIARRHYTHMIA AGENTS; ANTIDIABETIC AGENTS; ANTIPROLIFERATIVE AGENTS | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 2001-06-19 | — | — | US | disclosed |
| US-6169107-B1 | USEFUL FOR THE TREATMENT AND PREVENTION OF DISEASES CAUSED BY INCREASED SODIUM/PROTON (NA.SUP.+ /H.SUP.+) EXCHANGER ACTIVITY, FOR EXAMPLE, HYPERTENSION, ARRHYTHMIA, ANGINA PECTORIS, CARDIAC HYPERTROPHY, DIABETES MELLITUS | SUMITOMO PHARMACEUTICAL CO., LTD. (JP) | 2001-01-02 | — | — | US | disclosed |
| EP-0708091-A2 | Indoloylguanidine derivatives | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1996-04-24 | — | — | EP | disclosed |