SCHEMBL78852

SCHEMBL78852

CC(=O)c1ccc(OCCO)cc1

nearest known ligand 0.78

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.78
GAA P10253 2/20 0.75
MAPT P10636 5/20 0.64
ALDH1A1 P00352 2/20 0.64
NR1I2 O75469 1/20 0.61
LMNA P02545 2/20 0.59
POLB P06746 1/20 0.59
NPSR1 Q6W5P4 1/20 0.59
HPGD P15428 1/20 0.57
RAB9A P51151 1/20 0.57
MAOB P27338 7/20 0.56
MAOA P21397 1/20 0.53
HRH3 Q9Y5N1 1/20 0.53
RECQL P46063 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5114223 0.90 L3MBTL1 (0.81) L3MBTL1GAAMAPTALDH1A1LMNA
SCHEMBL834525 0.90 L3MBTL1 (0.88) L3MBTL1GAAMAPTALDH1A1LMNA
SCHEMBL3044200 0.89 L3MBTL1 (0.68) L3MBTL1GAAMAPTALDH1A1NR1I2
SCHEMBL28855980 0.89 L3MBTL1 (0.68) L3MBTL1GAAMAPTALDH1A1NR1I2
SCHEMBL3053864 0.89 L3MBTL1 (0.68) L3MBTL1GAAMAPTALDH1A1NR1I2
SCHEMBL7609908 0.89 L3MBTL1 (0.85) L3MBTL1GAAMAPTALDH1A1LMNA
SCHEMBL18868405 0.88 L3MBTL1 (1.00) L3MBTL1GAAMAPTALDH1A1LMNA
SCHEMBL3046764 0.86 L3MBTL1 (0.75) L3MBTL1GAAMAPTALDH1A1LMNA
SCHEMBL1092185 0.84 L3MBTL1 (0.85) L3MBTL1GAAMAPTALDH1A1LMNA
SCHEMBL8672706 0.84 L3MBTL1 (0.78) L3MBTL1GAAMAPTALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-9169699-A None JP disclosed
CN-118530734-A Liquid crystal aligning agent, liquid crystal alignment film, liquid crystal element, polymer, and compound JSR株式会社 2024-08-23 CN disclosed
CN-117751113-A Aromatic acetylene derivative and preparation method and application thereof 浙江海正药业股份有限公司 2024-03-22 CN disclosed
CN-117616070-A Emulsion preparation from polydimethylsiloxane mixtures by emulsion polymerization and influence on the formation of cyclics in the emulsion product 瓦克麦特罗克化学私营有限责任公司 2024-02-27 CN disclosed
US-11731967-B2 Inhibitors of TRIM33 and methods of use DANA-FARBER CANCER INSTITUTE, INC. (US) 2023-08-22 US disclosed
US-10351523-B2 UV-absorbing compounds with at least one reactive hydrogen ISP INVESTMENTS LLC 2019-07-16 US disclosed
US-10351523-B2 UV-absorbing compounds with at least one reactive hydrogen ISP INVESTMENTS LLC 2019-07-16 US disclosed
US-20180099927-A1 UV-ABSORBING COMPOUNDS WITH AT LEAST ONE REACTIVE HYDROGEN ISP INVESTMENTS LLC (US) 2018-04-12 US disclosed
US-20180099927-A1 UV-ABSORBING COMPOUNDS WITH AT LEAST ONE REACTIVE HYDROGEN ISP INVESTMENTS LLC (US) 2018-04-12 US disclosed
US-20180099927-A1 UV-ABSORBING COMPOUNDS WITH AT LEAST ONE REACTIVE HYDROGEN ISP INVESTMENTS LLC (US) 2018-04-12 US disclosed
EP-1067108-A2 Process for producing aryloxyacetic acids SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-01-10 EP disclosed
US-5892096-A CYANOACRYLIC DYES FOR PHOTORESISTS BREWER SCIENCE, INC. (US) 1999-04-06 US disclosed
US-5728706-A ENDOTHELIN ANTAGONISTS TANABE SEIYAKU CO., LTD. (JP) 1998-03-17 US disclosed
EP-0658548-B1 Benzenesulfonamide derivative and process for preparing thereof TANABE SEIYAKU CO (JP) 1997-11-19 EP disclosed
US-5688987-A PHOTORESISTS FOR SEMICONDUCTOR APPLICATIONS, ANTIREFLECTIVE COATINGS BREWER SCIENCE, INC. (US) 1997-11-18 US disclosed
JP-H09169699-A NEW DIBENZOYLMETHANE DERIVATIVE AND ITS PRODUCTION OSAKA ORGANIC CHEM IND LTD 1997-06-30 JP disclosed
US-5589478-A ENDOTHELIN ANTAGONISTS TANABE SEIYAKU CO., LTD. (JP) 1996-12-31 US disclosed
EP-0658548-A1 Benzenesulfonamide derivative and process for preparing thereof TANABE SEIYAKU CO., LTD. (JP) 1995-06-21 EP disclosed
US-5053509-A Microbiocides; AIDS LABORATOIRE ROGER BELLON (FR) 1991-10-01 US disclosed
US-4565769-A Polymeric sensitizers for photopolymer composition E. I. DU PONT DE NEMOURS AND COMPANY (US) 1986-01-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11731967-B2 Inhibitors of TRIM33 and methods of use TRIM33, TRIM28, TRIM4 L3MBTL1 487/4885GAA 1769/4885MAPT 1086/4885
US-10351523-B2 UV-absorbing compounds with at least one reactive hydrogen ERCC1, ERCC4, UNG L3MBTL1 4053/4885GAA 921/4885MAPT 596/4885
US-20180099927-A1 UV-ABSORBING COMPOUNDS WITH AT LEAST ONE REACTIVE HYDROGEN ERCC1, ERCC4, UNG L3MBTL1 4053/4885GAA 921/4885MAPT 596/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.