Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HHAT | Q5VTY9 | 2/20 | 0.66 |
| ▸ | LHCGR | P22888 | 5/20 | 0.54 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7888302 | 0.88 | MAPK1 (0.65) | HHATLHCGRMAPK1NPSR1 | |
| SCHEMBL7891997 | 0.88 | LHCGR (0.56) | HHATLHCGRMAPK1NPSR1 | |
| SCHEMBL7885827 | 0.88 | LHCGR (0.67) | HHATLHCGRMAPK1NPSR1 | |
| SCHEMBL7891893 | 0.88 | HHAT (0.66) | HHATLHCGRABCG2MAPK1NPSR1 | |
| SCHEMBL7880312 | 0.86 | HHAT (0.63) | HHATLHCGRMAPK1NPSR1 | |
| SCHEMBL8171464 | 0.85 | HHAT (0.51) | HHATLHCGRMAPK1NPSR1 | |
| SCHEMBL7891804 | 0.85 | LHCGR (0.64) | LHCGR | |
| SCHEMBL7891831 | 0.85 | HHAT (0.65) | HHATLHCGRMAPK1NPSR1 | |
| SCHEMBL7880265 | 0.85 | HHAT (0.65) | HHATLHCGRABCB1ABCG2 | |
| SCHEMBL7885990 | 0.85 | NPSR1 (0.51) | HHATLHCGRMAPK1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6177443-B1 | ANTIDIABETIC AGENTS | NOVO NORDISK A/S (DK) | 2001-01-23 | — | — | US | disclosed |
| EP-0973778-A1 | 4,5,6,7-TETRAHYDRO-THIENO 3,2-c]PYRIDINE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2000-01-26 | — | — | EP | disclosed |
| WO-1998040385-A1 | 4,5,6,7-TETRAHYDRO-THIENO[3,2-c]PYRIDINE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1998-09-17 | — | — | WO | disclosed |