Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LHCGR | P22888 | 11/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7891790 | 0.94 | POLB (0.69) | LHCGRPOLBMEN1KMT2ACNR1 | |
| SCHEMBL7885853 | 0.89 | LHCGR (0.73) | LHCGRPOLBMEN1KMT2A | |
| SCHEMBL7880463 | 0.89 | LHCGR (0.73) | LHCGRPOLBMEN1KMT2A | |
| SCHEMBL7880265 | 0.89 | HHAT (0.65) | LHCGRPOLBCA12CA1CA2 | |
| SCHEMBL7880417 | 0.89 | POLB (0.63) | LHCGRPOLB | |
| SCHEMBL7887385 | 0.89 | POLB (0.63) | LHCGRPOLBMEN1KMT2ACNR1 | |
| SCHEMBL7880530 | 0.89 | POLB (0.63) | LHCGRPOLB | |
| SCHEMBL7880311 | 0.88 | POLB (0.61) | LHCGRPOLBMEN1KMT2ACNR1 | |
| SCHEMBL7888190 | 0.88 | POLB (0.61) | LHCGRPOLBMEN1KMT2ACNR1 | |
| SCHEMBL7889885 | 0.88 | POLB (0.61) | LHCGRPOLBMEN1KMT2ACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6177443-B1 | ANTIDIABETIC AGENTS | NOVO NORDISK A/S (DK) | 2001-01-23 | — | — | US | disclosed |
| EP-0973778-A1 | 4,5,6,7-TETRAHYDRO-THIENO 3,2-c]PYRIDINE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2000-01-26 | — | — | EP | disclosed |
| WO-1998040385-A1 | 4,5,6,7-TETRAHYDRO-THIENO[3,2-c]PYRIDINE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1998-09-17 | — | — | WO | disclosed |