Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 8/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.56 |
| ▸ | PGR | P06401 | 7/20 | 0.56 |
| ▸ | LMNA | P02545 | 7/20 | 0.56 |
| ▸ | AR | P10275 | 6/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.56 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.56 |
| ▸ | USP2 | O75604 | 2/20 | 0.56 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | SHBG | P04278 | 1/20 | 0.56 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.56 |
| ▸ | HRH2 | P25021 | 1/20 | 0.56 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.56 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.56 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7885043 | 1.00 | NR3C1 (0.56) | NR3C1CYP3A4PGRLMNAAR | |
| SCHEMBL7885034 | 0.88 | NR3C1 (0.59) | NR3C1CYP3A4PGRLMNAAR | |
| SCHEMBL8722471 | 0.88 | NR3C1 (0.59) | NR3C1CYP3A4PGRLMNAAR | |
| SCHEMBL7887204 | 0.88 | NR3C1 (0.59) | NR3C1CYP3A4PGRLMNAAR | |
| SCHEMBL7882961 | 0.88 | NR3C1 (0.59) | NR3C1CYP3A4PGRLMNAAR | |
| SCHEMBL7882966 | 0.84 | NR3C1 (0.61) | NR3C1CYP3A4PGRLMNAAR | |
| SCHEMBL7887175 | 0.84 | NR3C1 (0.61) | NR3C1CYP3A4PGRLMNAAR | |
| SCHEMBL7887184 | 0.79 | PGR (0.65) | NR3C1CYP3A4PGRLMNAAR | |
| SCHEMBL7887183 | 0.78 | AR (0.58) | NR3C1CYP3A4PGRLMNAAR | |
| SCHEMBL8722476 | 0.75 | CYP3A4 (0.55) | NR3C1CYP3A4PGRLMNAAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6180803-B1 | STEROID DRUGS | LABORATOIRE THERAMEX (MC) | 2001-01-30 | — | — | US | disclosed |
| EP-0886645-B1 | NEW 19-NOR-PREGNENE DERIVATIVES | THERAMEX (MC) | 1999-09-01 | — | — | EP | disclosed |
| EP-0785212-A1 | New 19-nor-pregnene derivatives | LABORATOIRE THERAMEX (MC) | 1997-07-23 | — | — | EP | disclosed |