Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 16/20 | 0.56 |
| ▸ | MMP13 | P45452 | 16/20 | 0.56 |
| ▸ | MMP2 | P08253 | 4/20 | 0.53 |
| ▸ | MMP9 | P14780 | 4/20 | 0.53 |
| ▸ | MMP8 | P22894 | 3/20 | 0.53 |
| ▸ | MMP3 | P08254 | 2/20 | 0.53 |
| ▸ | MMP14 | P50281 | 2/20 | 0.51 |
| ▸ | MMP12 | P39900 | 1/20 | 0.51 |
| ▸ | FPR2 | P25090 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7134741 | 1.00 | MMP1 (0.56) | MMP1MMP13MMP2MMP9MMP8 | |
| SCHEMBL6998192 | 0.88 | MMP1 (0.71) | MMP1MMP13MMP2MMP9MMP8 | |
| SCHEMBL6998188 | 0.88 | MMP1 (0.71) | MMP1MMP13MMP2MMP9MMP8 | |
| SCHEMBL7141150 | 0.87 | MMP1 (0.58) | MMP1MMP13MMP2MMP9MMP8 | |
| SCHEMBL7886290 | 0.84 | MMP1 (0.62) | MMP1MMP13MMP2MMP9MMP8 | |
| SCHEMBL6946064 | 0.84 | MMP1 (0.70) | MMP1MMP13MMP2MMP9MMP8 | |
| SCHEMBL6796931 | 0.80 | MMP1 (0.58) | MMP1MMP13MMP2MMP9MMP8 | |
| SCHEMBL6801915 | 0.79 | MMP1 (0.59) | MMP1MMP13MMP2MMP9MMP8 | |
| SCHEMBL7213008 | 0.75 | MMP1 (0.55) | MMP1MMP13MMP2MMP9MMP8 | |
| SCHEMBL7213013 | 0.75 | MMP1 (0.55) | MMP1MMP13MMP2MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6214870-B1 | ANTIARTHRITIC AGENTS; ANTICANCER AGENTS | PFIZER INC | 2001-04-10 | — | — | US | disclosed |