Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 2/20 | 0.39 |
| ▸ | MMP13 | P45452 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | XBP1 | P17861 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7894997 | 0.90 | SLC6A9 (0.49) | SLC6A9MMP13CA2CA1CA4 | |
| SCHEMBL3711027 | 0.87 | SLC6A9 (0.44) | SLC6A9MEN1KMT2A | |
| SCHEMBL7896780 | 0.85 | SLC6A9 (0.55) | SLC6A9 | |
| SCHEMBL7895248 | 0.83 | SCN9A (0.34) | SLC6A9SCN9AKMT2AALDH1A1TSHR | |
| SCHEMBL7896254 | 0.83 | SCN9A (0.34) | SLC6A9SCN9AKMT2AALDH1A1TSHR | |
| SCHEMBL7895005 | 0.79 | SCN9A (0.34) | SLC6A9SCN9A | |
| SCHEMBL3705155 | 0.76 | SLC6A9 (0.55) | SLC6A9PHGDH | |
| SCHEMBL7893846 | 0.75 | SLC6A9 (0.68) | SLC6A9 | |
| SCHEMBL3709702 | 0.73 | SLC6A9 (0.41) | SLC6A9 | |
| SCHEMBL7899357 | 0.70 | MAPT (0.43) | SLC6A9SCN9AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010087761-A1 | 2-AZA-BICYCLO[2.2.2]OCTANE COMPOUNDS AND USES THEREOF | ASTRAZENECA AB (SE) | 2010-08-05 | — | — | WO | disclosed |