Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 13/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 5/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.32 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7896254 | 0.89 | SCN9A (0.34) | SCN9ASLC6A9 | |
| SCHEMBL7895248 | 0.89 | SCN9A (0.34) | SCN9ASLC6A9 | |
| SCHEMBL7894997 | 0.84 | SLC6A9 (0.49) | SCN9ASLC6A9 | |
| SCHEMBL7895234 | 0.80 | SLC6A9 (0.30) | SLC6A9 | |
| SCHEMBL3702719 | 0.80 | SLC6A9 (0.30) | SLC6A9 | |
| SCHEMBL7886491 | 0.79 | SLC6A9 (0.39) | SCN9ASLC6A9 | |
| SCHEMBL7899357 | 0.70 | MAPT (0.43) | SCN9ASLC6A9SLC6A5 | |
| SCHEMBL7893846 | 0.70 | SLC6A9 (0.68) | SLC6A9SLC6A5 | |
| SCHEMBL3785018 | 0.69 | — | — | |
| SCHEMBL7899349 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010087761-A1 | 2-AZA-BICYCLO[2.2.2]OCTANE COMPOUNDS AND USES THEREOF | ASTRAZENECA AB (SE) | 2010-08-05 | — | — | WO | disclosed |