Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT1 | P17948 | 2/20 | 0.53 |
| ▸ | FLT4 | P35916 | 2/20 | 0.53 |
| ▸ | KDR | P35968 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 2/20 | 0.43 |
| ▸ | JAK1 | P23458 | 1/20 | 0.43 |
| ▸ | TYK2 | P29597 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenol SCHEMBL27731559 | 0.89 | FLT1 (0.45) | FLT1FLT4KDRKDM4EALDH1A1 | |
| SCHEMBL28252825 | 0.87 | FLT1 (0.56) | FLT1FLT4KDRKDM4EALDH1A1 | |
| SCHEMBL12505398 | 0.86 | KDM4E (0.58) | FLT1FLT4KDRKDM4EALDH1A1 | |
| SCHEMBL27701739 | 0.85 | KDM4E (0.47) | KDM4EALDH1A1GLAGAAMAPT | |
| SCHEMBL17350872 | 0.85 | KDM4E (0.51) | KDM4EALDH1A1GLAGAAMAPT | |
| SCHEMBL28837661 | 0.84 | FLT1 (0.47) | FLT1FLT4KDRKDM4EALDH1A1 | |
| SCHEMBL30423630 | 0.84 | KDM4E (0.47) | FLT1FLT4KDRKDM4EALDH1A1 | |
| SCHEMBL28045482 | 0.83 | SIRT1 (0.46) | FLT1FLT4KDRKDM4EALDH1A1 | |
| SCHEMBL10290473 | 0.82 | HSD17B1 (0.56) | FLT1FLT4KDRKDM4EALDH1A1 | |
| SCHEMBL1548854 | 0.82 | SMN1; SMN2 (0.59) | FLT1FLT4KDRKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2200991-B1 | ANTIBACTERIAL AGENTS | BIOTA EUROPE LTD (GB) | 2011-03-23 | — | — | EP | disclosed |
| WO-2010102003-A2 | ALKYLSULFONYL-2,3-DIHYDROSPIRO[INDENE-1,4'-PIPERIDINE] ANALOGS AS GLYT1 INHIBITORS, METHODS FOR MAKING SAME, AND USE OF SAME IN TREATING PSYCHIATRIC DISORDERS | VANDERBILT UNIVERSITY (US) | 2010-09-10 | — | — | WO | disclosed |