Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.46 |
| ▸ | GRM1 | Q13255 | 7/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 6/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3441250 | 1.00 | MEN1 (0.47) | MEN1KMT2ACYP1A2CYP3A4GABRA1 | |
| SCHEMBL9420931 | 1.00 | MEN1 (0.47) | MEN1KMT2ACYP1A2CYP3A4GABRA1 | |
| SCHEMBL29672969 | 1.00 | MEN1 (0.47) | MEN1KMT2ACYP1A2CYP3A4GABRA1 | |
| SCHEMBL29672962 | 1.00 | MEN1 (0.47) | MEN1KMT2ACYP1A2CYP3A4GABRA1 | |
| SCHEMBL7886248 | 1.00 | MEN1 (0.47) | MEN1KMT2ACYP1A2CYP3A4GABRA1 | |
| SCHEMBL29419355 | 1.00 | MEN1 (0.47) | MEN1KMT2ACYP1A2CYP3A4GABRA1 | |
| Hydrochloric Acid SCHEMBL27551812 | 0.98 | MEN1 (0.46) | MEN1KMT2ACYP1A2CYP3A4GABRA1 | |
| SCHEMBL27557359 | 0.98 | MEN1 (0.46) | MEN1KMT2ACYP1A2CYP3A4GABRA1 | |
| Hydrochloric Acid SCHEMBL8615963 | 0.98 | MEN1 (0.46) | MEN1KMT2ACYP1A2CYP3A4GABRA1 | |
| Ethylene SCHEMBL8592522 | 0.96 | MEN1 (0.44) | MEN1KMT2ACYP1A2CYP3A4GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250275991-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | WILMINGTON TRUST, NATIONAL ASSOCIATION | 2025-09-04 | — | — | US | disclosed |
| EP-4041717-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | Biocryst Pharmaceuticals, Inc. (US) | 2022-08-17 | — | — | EP | disclosed |
| CN-114555570-A | Oral complement factor D inhibitors | 拜奥克里斯特制药公司 | 2022-05-27 | — | — | CN | disclosed |
| WO-2021072156-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2021-04-15 | — | — | WO | disclosed |
| EP-2454229-B1 | AMINO ACID DERIVATIVES FOR THE TREATMENT OF NEUROPATHIC PAIN | RISEN (SHANGHAI) PHARMA TECH CO LTD (CN) | 2017-09-13 | — | — | EP | disclosed |
| US-20160220519-A1 | AMINO ACID DERIVATIVES FOR THE TREATMENT OF NEUROPATHIC PAIN | LU, Jiasheng (CN) | 2016-08-04 | — | — | US | disclosed |
| US-20160220519-A1 | AMINO ACID DERIVATIVES FOR THE TREATMENT OF NEUROPATHIC PAIN | LU, Jiasheng (CN) | 2016-08-04 | — | — | US | disclosed |
| US-9233913-B2 | Amino acid derivatives for the treatment of neuropathic pain | Kong, Xianqi (CA) | 2016-01-12 | — | — | US | disclosed |
| US-9233913-B2 | Amino acid derivatives for the treatment of neuropathic pain | Kong, Xianqi (CA) | 2016-01-12 | — | — | US | disclosed |
| US-20140171507-A1 | AMINO ACID DERIVATIVES FOR THE TREATMENT OF NEUROPATHIC PAIN | Kong, Xianqi (CA) | 2014-06-19 | — | — | US | disclosed |
| US-20140171507-A1 | AMINO ACID DERIVATIVES FOR THE TREATMENT OF NEUROPATHIC PAIN | Kong, Xianqi (CA) | 2014-06-19 | — | — | US | disclosed |
| US-20120208876-A1 | AMINO ACID DERIVATIVES FOR THE TREATMENT OF NEUROPATHIC PAIN | Kong, Xianqi (CA) | 2012-08-16 | — | — | US | disclosed |
| US-20120208876-A1 | AMINO ACID DERIVATIVES FOR THE TREATMENT OF NEUROPATHIC PAIN | Kong, Xianqi (CA) | 2012-08-16 | — | — | US | disclosed |
| WO-2010127439-A1 | AMMO ACID DERIVATIVES FOR THE TREATMENT OF NEUROPATHIC PAIN | BELLUS HEALTH (INTERNATIONAL) LIMITED (CH) | 2010-11-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250275991-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | CFD, CFH, CFB | MEN1 659/4885KMT2A 4839/4885CYP1A2 2104/4885 |
| US-20140171507-A1 | AMINO ACID DERIVATIVES FOR THE TREATMENT OF NEUROPATHIC PAIN | GAP43, OPRL1, NGF | MEN1 4550/4885KMT2A 3055/4885CYP1A2 3871/4885 |
| US-20160220519-A1 | AMINO ACID DERIVATIVES FOR THE TREATMENT OF NEUROPATHIC PAIN | GAP43, OPRL1, NGF | MEN1 4553/4885KMT2A 3047/4885CYP1A2 3783/4885 |
| US-20120208876-A1 | AMINO ACID DERIVATIVES FOR THE TREATMENT OF NEUROPATHIC PAIN | GAP43, OPRL1, NGF | MEN1 4550/4885KMT2A 3055/4885CYP1A2 3871/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.