Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 5/20 | 0.56 |
| ▸ | PTPRC | P08575 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 13/20 | 0.44 |
| ▸ | CA1 | P00915 | 12/20 | 0.44 |
| ▸ | CA12 | O43570 | 9/20 | 0.44 |
| ▸ | CA9 | Q16790 | 9/20 | 0.44 |
| ▸ | CA5A | P35218 | 9/20 | 0.44 |
| ▸ | CA4 | P22748 | 8/20 | 0.44 |
| ▸ | CA7 | P43166 | 8/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 8/20 | 0.44 |
| ▸ | PTPRB | P23467 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | PLAT | P00750 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6950849 | 0.88 | PTPN1 (0.55) | PTPN1PTPRC | |
| SCHEMBL6951095 | 0.85 | PTPN1 (0.59) | PTPN1PTPRCF2PLAUPLAT | |
| SCHEMBL6946043 | 0.83 | CA2 (0.45) | CA2CA1CA12CA9CA5A | |
| SCHEMBL7888258 | 0.82 | PTPN1 (0.81) | PTPN1PTPRCCA2CA1PTPRB | |
| SCHEMBL6948365 | 0.79 | PTPN1 (0.49) | PTPN1PTPRCF2PLAUPLAT | |
| SCHEMBL6946443 | 0.78 | PTPN1 (0.53) | PTPN1PTPRCCA2CA1CA12 | |
| SCHEMBL6950094 | 0.78 | PTPN1 (0.48) | PTPN1PTPRC | |
| SCHEMBL6952150 | 0.71 | PTPN1 (1.00) | PTPN1PTPRCPTPRB | |
| SCHEMBL6952067 | 0.70 | PTPN1 (1.00) | PTPN1PTPRCPTPRB | |
| SCHEMBL6951489 | 0.70 | PTPN1 (1.00) | PTPN1PTPRCPTPRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6174874-B1 | ANTIDIABETIC,-CARCINOGENIC AGENTS; IMPROVING GLUCOSE TOLERANCE/INSULIN-SENSITIVITY; PREVENTING/TREATING OBESITY AND NEURODEGENERATIVE DISEASES; E.G. 1,3-BIS-((PHOSPHONODI-FLUOROMETHYL)PHENYL)-2-DICARBOXYPROPANE | MERCK FROSST CANADA & CO. (CA) | 2001-01-16 | — | — | US | disclosed |