Butane

Butane

SCHEMBL788832

CCCC.O=C(O)CC(=O)OCOC(=O)CC(=O)O

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGAM O43451 1/20 0.48
GAA P10253 1/20 0.48
SI P14410 1/20 0.48
MGAM2 Q2M2H8 1/20 0.48
LDHA P00338 1/20 0.40
SRR Q9GZT4 1/20 0.40
FFAR3 O14843 2/20 0.39
HDAC3 O15379 1/20 0.39
HDAC1 Q13547 1/20 0.39
HDAC2 Q92769 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
PAM P19021 2/20 0.39
ALDH1A1 P00352 4/20 0.36
TSHR P16473 4/20 0.36
EGLN1 Q9GZT9 1/20 0.35
FAAH O00519 1/20 0.35
AKR1B1 P15121 1/20 0.35
PPARG P37231 5/20 0.33
PPARD Q03181 5/20 0.33
PPARA Q07869 5/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL37772 0.89 LDHA (0.50) MGAMGAASIMGAM2LDHA
Butane SCHEMBL4659711 0.87 GAA (0.67) MGAMGAASIMGAM2LDHA
Butane SCHEMBL11738818 0.86 MGAM (0.46) MGAMGAASIMGAM2LDHA
SCHEMBL26462636 0.86 MGAM (0.48) MGAMGAASIMGAM2LDHA
Butane SCHEMBL452621 0.85 GAA (0.44) MGAMGAASIMGAM2LDHA
Ethylene SCHEMBL11358576 0.83 LDHA (0.44) MGAMGAASIMGAM2LDHA
Ethylene SCHEMBL3568811 0.83 LDHA (0.44) MGAMGAASIMGAM2LDHA
SCHEMBL4482991 0.82 ALDH1A1 (0.42) MGAMGAASIMGAM2LDHA
SCHEMBL240283 0.82 GAA (0.46) MGAMGAASIMGAM2LDHA
SCHEMBL12971698 0.82 MGAM (0.52) MGAMGAASIMGAM2LDHA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 494 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12005475-B2 Multi-layer curable compositions containing 1,1-di-activated vinyl compound products and related processes PPG INDUSTRIES OHIO, INC. (US) 2024-06-11 US claimed
US-11999866-B2 Polymalonate and cyanoacrylate based surface concrete sealers ZEPHYROS, INC. (US) 2024-06-04 US claimed
EP-3515994-B1 METHOD FOR SEALING POROUS SUBSTRATES ZEPHYROS INC (US) 2024-01-24 EP claimed
US-11859101-B2 Curable compositions containing 1,1-di-activated vinyl compounds and related coatings and processes PPG INDUSTRIES OHIO, INC. (US) 2024-01-02 US claimed
CN-115181277-B Preparation method of metal composite polymer single-chain nano particles 中国科学院化学研究所 2023-12-01 CN claimed
EP-3490724-B1 POLYURETHANE COATING COMPOSITIONS CONTAINING 1,1-DI-ACTIVATED VINYL COMPOUNDS AND RELATED COATINGS AND PROCESSES PPG IND OHIO INC (US) 2023-09-20 EP claimed
CN-112912451-B Curable coating composition SWIMC有限公司 2023-09-15 CN claimed
US-20230211551-A1 Three-Dimensional Printing Processes Using 1,1-Di-Activated Vinyl Compounds PPG INDUSTRIES OHIO, INC. (US) 2023-07-06 US claimed
US-20230201874-A1 MULTI-LAYER CURABLE COMPOSITIONS CONTAINING 1,1-DI-ACTIVATED VINYL COMPOUND PRODUCTS AND RELATED PROCESSES PPG INDUSTRIES OHIO, INC. 2023-06-29 US claimed
EP-3491079-B1 ELECTRODEPOSITABLE COATING COMPOSITIONS CONTAINING 1,1-DI-ACTIVATED VINYL COMPOUNDS PPG IND OHIO INC (US) 2023-06-07 EP claimed
US-20150361283-A1 INK COATING FORMULATIONS AND POLYMERIZABLE SYSTEMS FOR PRODUCING THE SAME NIPPON SHOKUBAI CO., LTD. (JP) 2015-12-17 US claimed
EP-2920231-A1 PLASTICS BONDING SYSTEMS AND METHODS Bioformix Inc. (US) 2015-09-23 EP claimed
US-20150210894-A1 PLASTICS BONDING SYSTEMS AND METHODS NIPPON SHOKUBAI CO., LTD. (JP) 2015-07-30 US claimed
WO-2014078689-A1 PLASTICS BONDING SYSTEMS AND METHODS BIOFORMIX INC. (US) 2014-05-22 WO claimed
CN-102758264-A Polymer nanofiber and preparation method and application of functional/hybrid material thereof CHINESE ACAD INST CHEMISTRY 2012-10-31 CN claimed
US-20120070642-A1 SAFETY GLAZINGS WITH IMPROVED WEATHERABILITY E.I. DU PONT DE NEMOURS AND COMPANY (US) 2012-03-22 US claimed
US-8080311-B2 Safety glazings with improved weatherability E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-12-20 US claimed
US-20100112343-A1 SAFETY GLAZINGS WITH IMPROVED WEATHERABILITY DOW GLOBAL TECHNOLOGIES LLC 2010-05-06 US claimed
CN-1132818-C 4-oxo-1, 4-dihydro-3-quinolinecarboxamides as antiviral agents PHARMACIA & UPJOHN CO. (US) 2003-12-31 CN claimed
CN-1332729-A 4-oxo-1,4-dihybro-3-quinolinecarboxamides as antiviral agents PHARMACIA & UP JOHN CO (US) 2002-01-23 CN claimed