Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.46 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.46 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.46 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CHAT | P28329 | 3/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7896695 | 0.87 | HPRT1 (0.58) | RXRATSHRHSD17B10ALDH1A1CYP2A6 | |
| SCHEMBL123180 | 0.80 | TSHR (0.48) | RXRATSHRHSD17B10ALDH1A1CYP2A6 | |
| SCHEMBL7897610 | 0.79 | ALDH1A1 (0.46) | RXRATSHRHSD17B10ALDH1A1TDP1 | |
| SCHEMBL10706700 | 0.79 | CHAT (0.62) | RXRATSHRHSD17B10ALDH1A1CYP2A6 | |
| SCHEMBL816177 | 0.79 | TSHR (0.50) | RXRATSHRHSD17B10ALDH1A1CYP2A6 | |
| SCHEMBL2494362 | 0.79 | TSHR (0.50) | RXRATSHRHSD17B10ALDH1A1CYP2A6 | |
| SCHEMBL10706687 | 0.79 | CHAT (0.62) | RXRATSHRHSD17B10ALDH1A1CYP2A6 | |
| SCHEMBL10706694 | 0.79 | CHAT (0.62) | RXRATSHRHSD17B10ALDH1A1CYP2A6 | |
| SCHEMBL10437274 | 0.77 | CHAT (0.60) | RXRACHATHDAC8HDAC6MTNR1A | |
| SCHEMBL10437275 | 0.77 | CHAT (0.60) | RXRACHATHDAC8HDAC6MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6183934-B1 | FOE USE IN FORMATION OF PATTERN OF INSULATION FILM, PASSIVATION FILM, .ALPHA.-RAY SHIELDING FILM, OPTICAL WAVEGUIDE | KABUSHIKI KAISHA TOSHIBA (JP) | 2001-02-06 | — | — | US | disclosed |