⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7895220 | 0.86 | — | — | |
| SCHEMBL7891384 | 0.84 | SIGMAR1 (0.30) | — | |
| SCHEMBL7883663 | 0.84 | IDO1 (0.31) | — | |
| SCHEMBL7883357 | 0.82 | IDO1 (0.31) | — | |
| SCHEMBL7883471 | 0.82 | IDO1 (0.31) | — | |
| SCHEMBL7890612 | 0.82 | — | — | |
| SCHEMBL7883171 | 0.81 | — | — | |
| SCHEMBL7883170 | 0.81 | — | — | |
| SCHEMBL8557065 | 0.81 | — | — | |
| SCHEMBL7890559 | 0.81 | ECE1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6180622-B1 | ANTIMICROBIAL ACTIVITY AGAINST A WIDE RANGE OF BACTERIA INCLUDING GRAM-POSITIVE BACTERIA, GRAM-NEGATIVE BACTERIA, BETA-LACTAMASE-PRODUCING BACTERIA, RESISTANT PSEUDOMONAS AERUGINOSA,METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS AND | MEIJI SEIKA KAISHA, LTD. (JP) | 2001-01-30 | — | — | US | disclosed |
| EP-0887352-A1 | CARBAPENEM DERIVATIVES AND ANTIMICROBIALS | MEIJI SEIKA KAISHA LTD. (JP) | 1998-12-30 | — | — | EP | disclosed |