SCHEMBL7888656

SCHEMBL7888656

COC(=O)c1ccc(C(OC)C(=O)O)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.62
L3MBTL1 Q9Y468 2/20 0.62
ALDH1A1 P00352 2/20 0.62
TSHR P16473 1/20 0.53
CA1 P00915 3/20 0.52
CA2 P00918 3/20 0.52
CA12 O43570 2/20 0.52
CA9 Q16790 2/20 0.52
CA14 Q9ULX7 2/20 0.52
TDP1 Q9NUW8 1/20 0.52
CA7 P43166 1/20 0.52
PPARA Q07869 2/20 0.51
RAB9A P51151 3/20 0.49
MAPT P10636 5/20 0.47
CASP3 P42574 1/20 0.47
SENP8 Q96LD8 1/20 0.47
SENP7 Q9BQF6 1/20 0.47
SENP6 Q9GZR1 1/20 0.47
LOXL2 Q9Y4K0 1/20 0.46
PPARG P37231 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5008293 0.84 GAA (0.56) GAAL3MBTL1ALDH1A1TSHRCA1
SCHEMBL15441153 0.81 TSHR (0.57) GAAL3MBTL1ALDH1A1TSHRCA1
SCHEMBL6950525 0.79 TSHR (0.55) L3MBTL1ALDH1A1TSHRCA1CA2
SCHEMBL11187333 0.79 TSHR (0.55) GAAL3MBTL1ALDH1A1TSHRCA1
SCHEMBL11187331 0.79 TSHR (0.55) GAAL3MBTL1ALDH1A1TSHRCA1
SCHEMBL11848919 0.79 PPARA (0.46) GAAL3MBTL1ALDH1A1PPARARAB9A
SCHEMBL5639207 0.79 CA1 (0.57) GAAL3MBTL1ALDH1A1TSHRCA1
SCHEMBL24327745 0.79 KEAP1 (0.55) GAAL3MBTL1ALDH1A1TDP1PPARA
SCHEMBL5040593 0.79 SRC (0.46) GAAL3MBTL1ALDH1A1TSHRCA1
SCHEMBL29069338 0.79 KEAP1 (0.41) GAAL3MBTL1ALDH1A1TSHRPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE37035-E1 HYPOGLYCEMIC AGENTS BOEHRINGER INGELHEIM KG (DE) 2001-01-30 US disclosed
US-6143769-A ENANTIOMORPH KARL THOMAE GMBH (DE) 2000-11-07 US disclosed
US-5312924-A Compounds for lowering blood sugar and effecting metabolism DR. KARL THOMAE GMBH (DE) 1994-05-17 US disclosed
US-5216167-A Hypoglycemic agents DR. KARL THOMAE GMBH (DE) 1993-06-01 US disclosed