Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.49 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.49 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.49 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6681989 | 0.86 | MAPT (0.55) | NQO1MAPTKDM4ECDK5CDK5R1 | |
| SCHEMBL11084906 | 0.79 | NQO1 (0.62) | NQO1MAPTKDM4ECDK5CDK5R1 | |
| SCHEMBL7129430 | 0.79 | TUBB1 (0.50) | MAPTKDM4ECDK5CDK5R1GAA | |
| SCHEMBL6224037 | 0.77 | MAPT (0.46) | MAPTKDM4ECDK5CDK5R1GAA | |
| SCHEMBL29017775 | 0.77 | MAPT (0.50) | MAPTKDM4ECDK5CDK5R1GAA | |
| SCHEMBL7092218 | 0.77 | NQO1 (0.50) | NQO1MAPTKDM4ECDK5CDK5R1 | |
| SCHEMBL4238902 | 0.76 | NQO1 (0.46) | NQO1MAPTKDM4ECDK5CDK5R1 | |
| SCHEMBL6273246 | 0.76 | MAPT (0.56) | MAPTKDM4ECDK5CDK5R1GAA | |
| SCHEMBL6667510 | 0.76 | MAPT (0.49) | MAPTKDM4ECDK5CDK5R1GAA | |
| SCHEMBL27744114 | 0.75 | PDE4A (0.48) | NQO1MAPTKDM4ECDK5CDK5R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6183934-B1 | FOE USE IN FORMATION OF PATTERN OF INSULATION FILM, PASSIVATION FILM, .ALPHA.-RAY SHIELDING FILM, OPTICAL WAVEGUIDE | KABUSHIKI KAISHA TOSHIBA (JP) | 2001-02-06 | — | — | US | disclosed |