SCHEMBL6667510

SCHEMBL6667510

COc1cc2cc(C)ccc2c(O)c1OC

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.49
POLB P06746 2/20 0.49
KDM4E B2RXH2 1/20 0.49
ABL1 P00519 1/20 0.49
GAA P10253 1/20 0.49
PKM P14618 1/20 0.49
APEX1 P27695 1/20 0.49
RECQL P46063 1/20 0.49
BLM P54132 1/20 0.49
CDK5 Q00535 1/20 0.49
MCL1 Q07820 1/20 0.49
RIN1 Q13671 1/20 0.49
CDK5R1 Q15078 1/20 0.49
SAE1 Q9UBE0 1/20 0.49
UBA2 Q9UBT2 1/20 0.49
TUBB4A P04350 3/20 0.46
TUBB P07437 3/20 0.46
TUBA3C P0DPH7 3/20 0.46
TUBA1B P68363 3/20 0.46
TUBA4A P68366 3/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6273246 0.86 MAPT (0.56) MAPTPOLBKDM4EABL1GAA
SCHEMBL29017775 0.84 MAPT (0.50) MAPTPOLBKDM4EABL1GAA
Methyl Alcohol SCHEMBL28281671 0.84 MAOA (0.47) MAPTPOLBKDM4EABL1GAA
SCHEMBL7129430 0.79 TUBB1 (0.50) MAPTPOLBKDM4EABL1GAA
SCHEMBL6681989 0.79 MAPT (0.55) MAPTPOLBKDM4EABL1GAA
SCHEMBL7889092 0.76 NQO1 (0.53) MAPTPOLBKDM4EABL1GAA
SCHEMBL21920120 0.75 CYP1A2 (0.50) MAPTKDM4EGAAACHETP53
SCHEMBL6224037 0.74 MAPT (0.46) MAPTPOLBKDM4EABL1GAA
SCHEMBL14421959 0.73 MAOA (0.54) MAPTPOLBKDM4EABL1GAA
SCHEMBL7196530 0.71 MAPT (0.47) MAPTPOLBKDM4EABL1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004014328-A1 ONE STEP HAIR COLORING COMPOSITIONS COMPRISING WATER SOLUBLE CARBONATE RELEASING SALTS UNILEVER PLC (GB) 2004-02-19 WO disclosed
WO-2003053386-A1 ENHANCED COLOUR DEPOSITION FOR HAIR WITH SEQUESTERING AGENTS UNILEVER PLC (GB) 2003-07-03 WO disclosed