SCHEMBL6681989

SCHEMBL6681989

COc1cc2ccccc2c(O)c1OC

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.55
KDM4E B2RXH2 3/20 0.55
ABL1 P00519 1/20 0.55
POLB P06746 1/20 0.55
GAA P10253 1/20 0.55
PKM P14618 1/20 0.55
APEX1 P27695 1/20 0.55
RECQL P46063 1/20 0.55
BLM P54132 1/20 0.55
CDK5 Q00535 1/20 0.55
MCL1 Q07820 1/20 0.55
RIN1 Q13671 1/20 0.55
CDK5R1 Q15078 1/20 0.55
SAE1 Q9UBE0 1/20 0.55
UBA2 Q9UBT2 1/20 0.55
ERN1 O75460 1/20 0.53
TUBB4A P04350 2/20 0.48
TUBB P07437 2/20 0.48
TUBA3C P0DPH7 2/20 0.48
TUBA1B P68363 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7889092 0.86 NQO1 (0.53) MAPTKDM4EABL1POLBGAA
SCHEMBL8082067 0.85 ERN1 (0.61) MAPTKDM4EABL1POLBGAA
SCHEMBL6545110 0.85 NQO1 (0.50) MAPTKDM4EGAACDK5MCL1
SCHEMBL28250998 0.83 ERN1 (0.54) MAPTKDM4EABL1POLBGAA
SCHEMBL7989542 0.83 MAPT (0.50) MAPTKDM4EGAACDK5CDK5R1
SCHEMBL2889415 0.82 MAOA (0.58) MAPTKDM4EABL1POLBGAA
SCHEMBL15212737 0.81 NQO1 (0.47) MAPTKDM4EGAACDK5CDK5R1
SCHEMBL27423013 0.81 MAOA (0.56) MAPTKDM4EABL1POLBGAA
SCHEMBL23043242 0.80 NQO1 (0.46) MAPTKDM4EGAACDK5CDK5R1
SCHEMBL30707088 0.80 NQO1 (0.46) MAPTKDM4EGAACDK5CDK5R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101475454-A Bionic synthesizing method for chemosterilant SHANDONG LONGLIVE BIO TECHNOLO (CN) 2009-07-08 CN disclosed
CN-100354253-C 5,8-menadiol diacetate derivatives and their preparing process and use SHANGHAI INST MATERIA MEDICA (CN) 2007-12-12 CN disclosed
CN-1690044-A 5,8-menadiol diacetate derivatives and their preparing process and use SHANGHAI INST MATERIA MEDICA (CN) 2005-11-02 CN disclosed
WO-2004014328-A1 ONE STEP HAIR COLORING COMPOSITIONS COMPRISING WATER SOLUBLE CARBONATE RELEASING SALTS UNILEVER PLC (GB) 2004-02-19 WO disclosed
WO-2003053386-A1 ENHANCED COLOUR DEPOSITION FOR HAIR WITH SEQUESTERING AGENTS UNILEVER PLC (GB) 2003-07-03 WO disclosed
EP-1214311-A1 NOVEL INDENO-FUSED PHOTOCHROMIC NAPHTHOPYRANS TRANSITIONS OPTICAL, INC. (US) 2002-06-19 EP disclosed
WO-2001019813-A1 NOVEL INDENO-FUSED PHOTOCHROMIC NAPHTHOPYRANS TRANSITIONS OPTICAL, INC. (US) 2001-03-22 WO disclosed
CN-1187811-A 1-[omega-(3,4-dihydro-2-naphthalenyl) alkyl] cyclic amine derivatives, process for producing same, and medicinal composition containing same DAINIPPON PHARMACEUTICAL CO (JP) 1998-07-15 CN disclosed