Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 4/20 | 0.38 |
| ▸ | LDHB | P07195 | 2/20 | 0.38 |
| ▸ | CPN1 | P15169 | 1/20 | 0.36 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.36 |
| ▸ | MLNR | O43193 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | CTSD | P07339 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | PGA5 | P0DJD9 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | CTSE | P14091 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | CCKAR | P32238 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6948749 | 0.81 | MLNR (0.49) | LDHALDHBCPN1CPB2MLNR | |
| SCHEMBL6175249 | 0.79 | MLNR (0.41) | LDHAMLNRNR1I2ABCB11PGR | |
| SCHEMBL6173274 | 0.78 | OPRD1 (0.39) | LDHAMLNRNR1I2ABCB11PGR | |
| SCHEMBL7409452 | 0.76 | MLNR (0.43) | CPN1CPB2MLNRNR1I2ABCB11 | |
| SCHEMBL6957401 | 0.75 | MLNR (0.58) | LDHALDHBCPN1CPB2MLNR | |
| SCHEMBL1324788 | 0.75 | MLNR (0.58) | LDHALDHBCPN1CPB2MLNR | |
| SCHEMBL6958382 | 0.75 | MLNR (0.58) | LDHALDHBCPN1CPB2MLNR | |
| SCHEMBL6954624 | 0.75 | MLNR (0.58) | LDHALDHBCPN1CPB2MLNR | |
| SCHEMBL6175172 | 0.74 | LDHA (0.38) | LDHAMLNRNR1I2ABCB11PGR | |
| SCHEMBL7405985 | 0.73 | CYP1A2 (0.37) | MLNRNR1I2ABCB11PGRCTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6169181-B1 | HUMAN IMMUNODEFICIENCY VIRUS PROTEINASE INHIBITORS | PHARMACIA & UPJOHN COMPANY | 2001-01-02 | — | — | US | disclosed |
| US-5852195-A | Pyranone compounds useful to treat retroviral infections | PHARMACIA & UPJOHN COMPANY (US) | 1998-12-22 | — | — | US | disclosed |