Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 4/20 | 0.55 |
| ▸ | CA2 | P00918 | 4/20 | 0.55 |
| ▸ | CA9 | Q16790 | 4/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.55 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.54 |
| ▸ | MMP1 | P03956 | 5/20 | 0.52 |
| ▸ | MMP2 | P08253 | 5/20 | 0.52 |
| ▸ | MMP9 | P14780 | 5/20 | 0.52 |
| ▸ | MMP12 | P39900 | 5/20 | 0.52 |
| ▸ | MMP14 | P50281 | 5/20 | 0.52 |
| ▸ | MMP15 | P51511 | 5/20 | 0.52 |
| ▸ | MMP16 | P51512 | 5/20 | 0.52 |
| ▸ | MMP26 | Q9NRE1 | 5/20 | 0.52 |
| ▸ | MMP7 | P09237 | 4/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3394741 | 0.84 | MMP1 (0.70) | MEN1KMT2ATAS2R14MMP1MMP2 | |
| SCHEMBL3397104 | 0.84 | MMP1 (0.70) | MEN1KMT2ATAS2R14MMP1MMP2 | |
| SCHEMBL3392159 | 0.84 | MMP1 (0.70) | MEN1KMT2ATAS2R14MMP1MMP2 | |
| SCHEMBL3393324 | 0.84 | MMP1 (0.70) | MEN1KMT2ATAS2R14MMP1MMP2 | |
| SCHEMBL3397077 | 0.79 | RYR2 (0.51) | MEN1KMT2ACA1CA2CA9 | |
| SCHEMBL29052386 | 0.78 | MEN1 (0.57) | MEN1KMT2ACA1CA2CA9 | |
| SCHEMBL3393154 | 0.76 | MEN1 (0.60) | MEN1KMT2ACA1CA2CA9 | |
| SCHEMBL3393158 | 0.76 | MEN1 (0.60) | MEN1KMT2ACA1CA2CA9 | |
| SCHEMBL29051730 | 0.76 | CA1 (0.48) | MEN1KMT2ACA1CA2CA9 | |
| SCHEMBL1016818 | 0.72 | PKM (0.62) | MEN1KMT2ALMNARYR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2246331-A1 | NR2B-selective NMDA-receptor antagonists | Westfälische Wilhelms-Universität Münster (DE) | 2010-11-03 | — | — | EP | disclosed |
| WO-2010122134-A1 | NR2B-SELECTIVE NMDA-RECEPTOR ANTAGONISTS | Westfälische Wilhelms Universität Münster (DE) | 2010-10-28 | — | — | WO | disclosed |