Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.64 |
| ▸ | MPO | P05164 | 4/20 | 0.54 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | XDH | P47989 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8520728 | 0.78 | ALDH1A1 (0.60) | ALDH1A1MPOSMN1; SMN2LMNAXDH | |
| SCHEMBL2731278 | 0.78 | ALDH1A1 (0.75) | ALDH1A1MPOSMN1; SMN2XDHHSD17B10 | |
| SCHEMBL7102614 | 0.78 | CA12 (0.61) | ALDH1A1MPOSMN1; SMN2LMNAXDH | |
| SCHEMBL18708215 | 0.78 | ALDH1A1 (1.00) | ALDH1A1MPOLMNAMAPK1XDH | |
| SCHEMBL8519883 | 0.77 | ALDH1A1 (0.59) | ALDH1A1MPOHAVCR2SMN1; SMN2LMNA | |
| SCHEMBL8519360 | 0.75 | CA12 (0.57) | ALDH1A1MPOSMN1; SMN2LMNAXDH | |
| SCHEMBL12713432 | 0.74 | MPO (0.73) | ALDH1A1MPOHAVCR2SMN1; SMN2XDH | |
| SCHEMBL29446410 | 0.73 | KCNH2 (0.69) | ALDH1A1MPOHAVCR2SMN1; SMN2NPC1 | |
| SCHEMBL29446426 | 0.71 | ALDH1A1 (0.52) | ALDH1A1MPOHAVCR2SMN1; SMN2LMNA | |
| SCHEMBL15958274 | 0.71 | ALDH1A1 (0.63) | ALDH1A1MPOSMN1; SMN2LMNAXDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245770-B1 | AGRICULTURE | E. I. DU PONT DE NEMOURS AND COMPANY | 2001-06-12 | — | — | US | disclosed |
| US-6066638-A | CONTROLLING PLANT DISEASES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-05-23 | — | — | US | disclosed |