SCHEMBL789038 — predicted protein targets

Predicted protein targets (top 15)

	gene	UniProt	supporting neighbours	confidence
▸	TRPC3	Q13507	11/20	0.77

▸	TRPC6	Q9Y210	11/20	0.77

▸	TRPA1	O75762	2/20	0.77

▸	CACNA1C	Q13936	2/20	0.77

▸	SCN5A	Q14524	2/20	0.77

▸	TRPV1	Q8NER1	2/20	0.77

▸	TRPV4	Q9HBA0	2/20	0.77

▸	HCRTR1	O43613	5/20	0.36

▸	P2RX3	P56373	1/20	0.36

▸	ACACB	O00763	1/20	0.35

▸	ALDH1A1	P00352	1/20	0.35

▸	MAPT	P10636	1/20	0.35

▸	SMN1; SMN2	Q16637	1/20	0.35

▸	CPS1	P31327	1/20	0.35

▸	HCRTR2	O43614	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL26458205	0.88	TRPC3 (0.83)	TRPC3TRPC6TRPA1CACNA1CSCN5A
SCHEMBL26458213	0.88	TRPC3 (0.83)	TRPC3TRPC6TRPA1CACNA1CSCN5A
SCHEMBL26459111	0.87	TRPC3 (1.00)	TRPC3TRPC6TRPA1CACNA1CSCN5A
SCHEMBL798463	0.87	TRPC3 (1.00)	TRPC3TRPC6TRPA1CACNA1CSCN5A
SCHEMBL788988	0.84	TRPC3 (0.59)	TRPC3TRPC6TRPA1CACNA1CSCN5A
SCHEMBL806600	0.81	TRPC3 (1.00)	TRPC3TRPC6TRPA1CACNA1CSCN5A
SCHEMBL806710	0.78	TRPC3 (0.65)	TRPC3TRPC6TRPA1CACNA1CSCN5A
SCHEMBL798400	0.78	TRPC3 (0.65)	TRPC3TRPC6TRPA1CACNA1CSCN5A
SCHEMBL26458201	0.78	TRPC3 (0.80)	TRPC3TRPC6TRPA1CACNA1CSCN5A
SCHEMBL806647	0.76	TRPC3 (0.54)	TRPC3TRPC6TRPA1CACNA1CSCN5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2012037351-A1	COMPOUNDS	GLAXOSMITHKLINE LLC (US)	2012-03-22	—	—	WO	disclosed