Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC3 | Q13507 | 9/20 | 0.65 |
| ▸ | TRPC6 | Q9Y210 | 9/20 | 0.65 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.65 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.65 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.65 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.65 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.65 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.41 |
| ▸ | GALR1 | P47211 | 4/20 | 0.41 |
| ▸ | GALR2 | O43603 | 4/20 | 0.41 |
| ▸ | SCD | O00767 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL798400 | 1.00 | TRPC3 (0.65) | TRPC3TRPC6TRPA1CACNA1CSCN5A | |
| SCHEMBL806708 | 0.83 | TRPC3 (0.68) | TRPC3TRPC6TRPA1CACNA1CSCN5A | |
| SCHEMBL26458213 | 0.80 | TRPC3 (0.83) | TRPC3TRPC6TRPA1CACNA1CSCN5A | |
| SCHEMBL26458205 | 0.80 | TRPC3 (0.83) | TRPC3TRPC6TRPA1CACNA1CSCN5A | |
| SCHEMBL798463 | 0.79 | TRPC3 (1.00) | TRPC3TRPC6TRPA1CACNA1CSCN5A | |
| SCHEMBL26459111 | 0.79 | TRPC3 (1.00) | TRPC3TRPC6TRPA1CACNA1CSCN5A | |
| SCHEMBL30186173 | 0.79 | TRPC3 (1.00) | TRPC3TRPC6TRPA1CACNA1CSCN5A | |
| SCHEMBL789038 | 0.78 | TRPC3 (0.77) | TRPC3TRPC6TRPA1CACNA1CSCN5A | |
| SCHEMBL806600 | 0.77 | TRPC3 (1.00) | TRPC3TRPC6TRPA1CACNA1CSCN5A | |
| SCHEMBL26458201 | 0.75 | TRPC3 (0.80) | TRPC3TRPC6TRPA1CACNA1CSCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037351-A1 | COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |