Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.54 |
| ▸ | CES2 | O00748 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CCR5 | P51681 | 11/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | USP19 | O94966 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL427359 | 0.89 | FAAH (0.52) | FAAHCES2KCNH2DRD2DRD4 | |
| SCHEMBL428068 | 0.88 | FAAH (0.46) | FAAHCES2CCR5MCHR1 | |
| SCHEMBL424816 | 0.87 | DRD2 (0.57) | FAAHCES2KCNH2DRD2DRD4 | |
| SCHEMBL7893697 | 0.85 | FAAH (0.52) | FAAHCES2POLBCCR5USP19 | |
| SCHEMBL12473853 | 0.84 | FAAH (0.58) | FAAHCES2POLBUSP19GPR119 | |
| SCHEMBL427415 | 0.83 | DRD2 (0.52) | FAAHCES2KCNH2DRD2DRD4 | |
| SCHEMBL427987 | 0.83 | FAAH (0.42) | FAAHCES2CCR5KCNH2MCHR1 | |
| SCHEMBL424383 | 0.83 | FAAH (0.74) | FAAHCES2POLBUSP19 | |
| SCHEMBL424977 | 0.83 | FAAH (0.50) | FAAHCES2CCR5DRD2DRD4 | |
| SCHEMBL425070 | 0.83 | FAAH (0.50) | FAAHCES2DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010074588-A2 | PHARMACEUTICAL COMPOUNDS | BIAL - PORTELA & Cª, S.A. (PT) | 2010-07-01 | — | — | WO | disclosed |