Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | CTSD | P07339 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 8/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.42 |
| ▸ | CASP1 | P29466 | 3/20 | 0.42 |
| ▸ | CASP7 | P55210 | 3/20 | 0.42 |
| ▸ | GLA | P06280 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7888390 | 0.88 | ALDH1A1 (0.49) | ALDH1A1TSHRCTSDKDM4ECYP1A2 | |
| SCHEMBL5712371 | 0.86 | ALDH1A1 (0.39) | ALDH1A1TSHRHTTCYP2D6MAPK1 | |
| SCHEMBL5712356 | 0.81 | MAPK1 (0.45) | ALDH1A1TSHRKDM4EHTTMEN1 | |
| SCHEMBL21925 | 0.80 | USP2 (0.47) | ALDH1A1TSHRHTTMEN1KMT2A | |
| SCHEMBL8406727 | 0.79 | USP2 (0.46) | ALDH1A1TSHRHTTMEN1KMT2A | |
| SCHEMBL8406726 | 0.78 | USP2 (0.45) | ALDH1A1TSHRHTTMEN1KMT2A | |
| SCHEMBL7889964 | 0.76 | TP53 (0.48) | ALDH1A1KDM4EHTTATMPOLB | |
| SCHEMBL5712378 | 0.76 | TDP1 (0.42) | ALDH1A1TSHRKDM4EHSD17B10HTT | |
| SCHEMBL5712352 | 0.75 | PARG (0.42) | ALDH1A1TSHRHTTGAAMEN1 | |
| SCHEMBL8018051 | 0.73 | CYP2D6 (0.42) | ALDH1A1CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0836602-A1 | FUNGICIDAL PYRIMIDINONES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-04-22 | — | — | EP | claimed |
| WO-1997002262-A1 | FUNGICIDAL PYRIMIDINONES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-01-23 | — | — | WO | claimed |
| US-6245770-B1 | AGRICULTURE | E. I. DU PONT DE NEMOURS AND COMPANY | 2001-06-12 | — | — | US | disclosed |
| US-6066638-A | CONTROLLING PLANT DISEASES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-05-23 | — | — | US | disclosed |
| EP-0836602-A1 | FUNGICIDAL PYRIMIDINONES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-04-22 | — | — | EP | disclosed |
| WO-1997002262-A1 | FUNGICIDAL PYRIMIDINONES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-01-23 | — | — | WO | disclosed |