Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARG | Q86W56 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | NPY1R | P25929 | 1/20 | 0.41 |
| ▸ | NPY2R | P49146 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 3/20 | 0.36 |
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21925 | 0.87 | USP2 (0.47) | PARGALDH1A1LMNAL3MBTL1NPY1R | |
| SCHEMBL8406727 | 0.86 | USP2 (0.46) | PARGALDH1A1LMNAL3MBTL1NPY1R | |
| SCHEMBL5712356 | 0.86 | MAPK1 (0.45) | PARGALDH1A1LMNAL3MBTL1NPY1R | |
| SCHEMBL8406726 | 0.85 | USP2 (0.45) | PARGALDH1A1LMNAL3MBTL1NPY1R | |
| SCHEMBL5712378 | 0.81 | TDP1 (0.42) | PARGALDH1A1LMNAL3MBTL1NPY1R | |
| SCHEMBL5712371 | 0.80 | ALDH1A1 (0.39) | PARGALDH1A1LMNAL3MBTL1NPY1R | |
| SCHEMBL5712394 | 0.78 | MTNR1A (0.40) | PARGALDH1A1LMNAL3MBTL1NPY1R | |
| SCHEMBL5712361 | 0.76 | ADORA2B (0.40) | ALDH1A1TSHRMAPK1SMN1; SMN2 | |
| SCHEMBL7892011 | 0.75 | ALDH1A1 (0.46) | ALDH1A1TSHRMAPK1USP2HTT | |
| Pyrimethanil SCHEMBL302650 | 0.74 | CDK4 (0.44) | ALDH1A1LMNAL3MBTL1NPY1RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1344775-B1 | Preparation of fungicidal quinazolinones and useful intermediates | DU PONT (US) | 2006-11-29 | — | — | EP | disclosed |
| EP-0922037-B1 | PREPARATION OF FUNGICIDAL QUINAZOLINONES AND USEFUL INTERMEDIATES | DU PONT (US) | 2003-10-01 | — | — | EP | disclosed |
| EP-1344775-A1 | Preparation of fungicidal quinazolinones and useful intermediates | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-09-17 | — | — | EP | disclosed |