Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.76 |
| ▸ | USP2 | O75604 | 1/20 | 0.76 |
| ▸ | POLB | P06746 | 1/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.76 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | GAPDH | P04406 | 2/20 | 0.39 |
| ▸ | HRAS | P01112 | 1/20 | 0.39 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 2/20 | 0.37 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29324579 | 0.89 | MEN1 (0.76) | MEN1USP2POLBKMT2ALMNA | |
| SCHEMBL29324578 | 0.87 | MEN1 (1.00) | MEN1USP2POLBKMT2ALMNA | |
| SCHEMBL11789048 | 0.87 | MEN1 (1.00) | MEN1USP2POLBKMT2ALMNA | |
| SCHEMBL10887751 | 0.78 | MEN1 (0.76) | MEN1USP2POLBKMT2ALMNA | |
| SCHEMBL10887745 | 0.78 | MEN1 (0.76) | MEN1USP2POLBKMT2ALMNA | |
| SCHEMBL7896853 | 0.78 | ALDH1A1 (0.52) | MEN1USP2POLBKMT2ALMNA | |
| SCHEMBL29323294 | 0.76 | MEN1 (0.80) | MEN1USP2POLBKMT2ALMNA | |
| SCHEMBL20256018 | 0.75 | PTPN1 (0.48) | MEN1USP2POLBKMT2AALDH1A1 | |
| SCHEMBL21651039 | 0.75 | PTPN1 (0.48) | MEN1USP2POLBKMT2AALDH1A1 | |
| SCHEMBL18654281 | 0.75 | PTPN1 (0.48) | MEN1USP2POLBKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1027359-A4 | MONOCYCLIC L-NUCLEOSIDES, ANALOGS AND USES THEREOF | ICN PHARMACEUTICALS (US) | 2001-07-25 | — | — | EP | disclosed |
| EP-1027359-A2 | MONOCYCLIC L-NUCLEOSIDES, ANALOGS AND USES THEREOF | ICN Pharmaceuticals, Inc. (US) | 2000-08-16 | — | — | EP | disclosed |
| WO-1998016186-A2 | MONOCYCLIC L-NUCLEOSIDES, ANALOGS AND USES THEREOF | ICN PHARMACEUTICALS, INC. (US) | 1998-04-23 | — | — | WO | disclosed |