Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | GMNN | O75496 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.52 |
| ▸ | THPO | P40225 | 1/20 | 0.52 |
| ▸ | MTOR | P42345 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | HBB | P68871 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PNP | P00491 | 1/20 | 0.45 |
| ▸ | GSK3A | P49840 | 4/20 | 0.45 |
| ▸ | RPS6KA3 | P51812 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2295858 | 0.87 | MEN1 (0.58) | ALDH1A1HTTGMNNLMNATP53 | |
| SCHEMBL13376162 | 0.87 | MEN1 (0.58) | ALDH1A1HTTGMNNLMNATP53 | |
| SCHEMBL10057756 | 0.87 | MEN1 (0.58) | ALDH1A1HTTGMNNLMNATP53 | |
| SCHEMBL13019185 | 0.87 | MEN1 (0.58) | ALDH1A1HTTGMNNLMNATP53 | |
| SCHEMBL20078065 | 0.87 | MEN1 (0.58) | ALDH1A1HTTGMNNLMNATP53 | |
| SCHEMBL15705224 | 0.87 | MEN1 (0.58) | ALDH1A1HTTGMNNLMNATP53 | |
| SCHEMBL7892283 | 0.78 | MEN1 (0.76) | ALDH1A1HTTLMNAMEN1USP2 | |
| SCHEMBL10260643 | 0.78 | MEN1 (0.58) | ALDH1A1HTTLMNATP53MEN1 | |
| SCHEMBL15702572 | 0.78 | MEN1 (0.58) | ALDH1A1HTTLMNATP53MEN1 | |
| SCHEMBL524073 | 0.77 | LMNA (0.79) | ALDH1A1HTTGMNNLMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1027359-A4 | MONOCYCLIC L-NUCLEOSIDES, ANALOGS AND USES THEREOF | ICN PHARMACEUTICALS (US) | 2001-07-25 | — | — | EP | disclosed |
| EP-1027359-A2 | MONOCYCLIC L-NUCLEOSIDES, ANALOGS AND USES THEREOF | ICN Pharmaceuticals, Inc. (US) | 2000-08-16 | — | — | EP | disclosed |
| WO-1998016186-A2 | MONOCYCLIC L-NUCLEOSIDES, ANALOGS AND USES THEREOF | ICN PHARMACEUTICALS, INC. (US) | 1998-04-23 | — | — | WO | disclosed |