Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CACNA1G | O43497 | 6/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7893126 | 0.80 | S1PR3 (0.41) | ABCB1MEN1KMT2A | |
| SCHEMBL7893034 | 0.80 | ABCB1 (0.38) | ABCB1MEN1KMT2AGRM5GRM2 | |
| SCHEMBL5924622 | 0.71 | SMN1; SMN2 (0.34) | ABCB1MEN1KMT2AGRM5 | |
| SCHEMBL22636046 | 0.66 | MEN1 (0.37) | ABCB1MEN1KMT2AGRM5 | |
| SCHEMBL9233266 | 0.66 | TAAR1 (0.31) | EPHX1 | |
| SCHEMBL24311920 | 0.65 | SMN1; SMN2 (0.43) | ABCB1MEN1KMT2AALDH1A1GRM5 | |
| SCHEMBL6160152 | 0.64 | MAPT (0.43) | MEN1KMT2AALDH1A1GRM5 | |
| SCHEMBL6160158 | 0.64 | MAPT (0.43) | MEN1KMT2AALDH1A1GRM5 | |
| SCHEMBL5252120 | 0.64 | MAPT (0.43) | MEN1KMT2AALDH1A1GRM5 | |
| SCHEMBL18667255 | 0.64 | CACNA1G (0.44) | ABCB1CACNA1GCYP3A4CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6319702-B1 | NUCLEOTIDE SEQUENCS CODING AN ENZYMATIC POLYPEPTIDE AND CELL TARGETING COMPOUND; FOR USE IN TREATMENT OF CANCER | GLAXO WELLCOME, INC. | 2001-11-20 | — | — | US | disclosed |