SCHEMBL789434

SCHEMBL789434

[O-][n+]1cc(Br)cc2cc(Cl)ccc21

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AHR P35869 2/20 0.35
CYP2A6 P11509 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17913534 0.85 AHR (0.35) AHRCYP2A6
SCHEMBL1285478 0.75 ATM (0.50) AHRCYP2A6
SCHEMBL18571737 0.70 AHR (0.35) AHRCYP2A6
SCHEMBL21988773 0.70 ERN1 (0.34) AHRCYP2A6
SCHEMBL1826895 0.69 CYP2A6 (0.45) AHRCYP2A6
SCHEMBL17442670 0.68 TTR (0.30)
SCHEMBL8512795 0.67 ATM (0.50) AHRCYP2A6
SCHEMBL18572343 0.67
SCHEMBL30948828 0.67 MEN1 (0.38) AHRCYP2A6
SCHEMBL1249703 0.66 CYP2A6 (0.56) AHRCYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012037108-A1 AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS GLAXOSMITHKLINE LLC (US) 2012-03-22 WO disclosed