Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 3/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CASP6 | P55212 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TERT | O14746 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | AHR | P35869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7479947 | 0.75 | ATM (0.50) | ATMKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL2796407 | 0.75 | ATM (0.50) | ATMCYP2A6KMT2AMEN1RAB9A | |
| SCHEMBL4164409 | 0.75 | ATM (0.50) | ATMKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL1394239 | 0.75 | ATM (0.50) | ATMKMT2AMEN1RAB9AGAA | |
| SCHEMBL1285478 | 0.75 | ATM (0.50) | ATMCYP2A6KMT2AMEN1RAB9A | |
| SCHEMBL25413825 | 0.75 | ATM (0.50) | ATMCYP2A6KMT2AMEN1RAB9A | |
| SCHEMBL13806417 | 0.75 | ATM (0.50) | ATMKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL18571737 | 0.75 | AHR (0.35) | CYP2A6KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL1826895 | 0.73 | CYP2A6 (0.45) | ATMCYP2A6KMT2AMEN1GAA | |
| SCHEMBL2008748 | 0.73 | PARP1 (0.50) | ATMKMT2AMEN1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110256342-B | Synthetic method of 2-cyano quinoline derivative | 河南省科学院化学研究所有限公司 | 2022-06-07 | — | — | CN | disclosed |
| CN-110256342-A | A kind of synthetic method of 2- cyano-quinoline derivatives | 河南省科学院化学研究所有限公司 | 2019-09-20 | — | — | CN | disclosed |
| WO-2012069856-A1 | ANTIMALARIAL COMPOUNDS | LIVERPOOL SCHOOL OF TROPICAL MEDICINE (GB) | 2012-05-31 | — | — | WO | disclosed |