SCHEMBL7894657

SCHEMBL7894657

CC(OP(=O)(O)O)C(C)(C)N

nearest known ligand 0.40

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FDPS P14324 2/20 0.40
GRM4 Q14833 1/20 0.33
SMPD1 P17405 5/20 0.32
LAP3 P28838 1/20 0.32
LMNA P02545 1/20 0.31
METAP1 P53582 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL466569 0.80 LAP3 (0.35) FDPSSMPD1LAP3LMNA
SCHEMBL20644376 0.73 CTSA (0.35) FDPSSMPD1
SCHEMBL10595209 0.73 CYP2C19 (0.38) FDPSSMPD1LMNA
SCHEMBL15453973 0.73 KDM4E (0.32) SMPD1
SCHEMBL526263 0.73 SMPD1 (0.34) SMPD1
SCHEMBL30314553 0.70 CTSA (0.32) SMPD1
Phosphoric Acid SCHEMBL14782505 0.69 FDPS (0.48) FDPSGRM4LAP3LMNAMETAP1
SCHEMBL63997 0.69
SCHEMBL38660292 0.69 CA12 (0.33)
SCHEMBL28327052 0.68 LAP3 (0.39) FDPSGRM4SMPD1LAP3LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1128784-A1 THERAPEUTIC USE OF POLYMERS BIOCOMPATIBLES LTD. (GB) 2001-09-05 EP disclosed
WO-2000028920-A1 THERAPEUTIC USE OF POLYMERS BIOCOMPATIBLES LIMITED (GB) 2000-05-25 WO disclosed