Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.40 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.40 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.40 |
| ▸ | CDK4 | P11802 | 1/20 | 0.40 |
| ▸ | CCND1 | P24385 | 1/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| (Z)-1,2-Diphenylethene SCHEMBL20495486 | 0.85 | MEN1 (0.44) | MEN1KMT2ACHRNB4CHRNA3HRH3 | |
| SCHEMBL158812 | 0.82 | — | — | |
| SCHEMBL1132942 | 0.82 | — | — | |
| Ammonia Solution, Strong SCHEMBL1327720 | 0.80 | — | — | |
| Biphenyl SCHEMBL27478734 | 0.77 | SPHK1 (0.64) | CYP2D6SPHK1SPHK2PDCD1CD274 | |
| SCHEMBL8565864 | 0.76 | MC4R (0.46) | — | |
| SCHEMBL11466316 | 0.76 | MC4R (0.46) | — | |
| SCHEMBL16765733 | 0.76 | — | — | |
| SCHEMBL12530064 | 0.76 | SPHK1 (0.63) | CYP2D6SPHK1SPHK2PDCD1CD274 | |
| SCHEMBL2269998 | 0.76 | SPHK1 (0.63) | CYP2D6SPHK1SPHK2PDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6180837-B1 | Process for the catalytic enantioselective reduction of ketones | DEGUSSA-HUELS AG (DE) | 2001-01-30 | — | — | US | disclosed |