(Z)-1,2-Diphenylethene

(Z)-1,2-Diphenylethene

SCHEMBL20495486

C(=C/c1ccccc1)\c1ccccc1.OCC1CCCN1O

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
CHRNB1 P11230 1/20 0.41
CHRNB2 P17787 1/20 0.41
CHRNB4 P30926 1/20 0.41
CHRNA3 P32297 1/20 0.41
CHRNB3 Q05901 1/20 0.41
HRH3 Q9Y5N1 1/20 0.40
SLC18A2 Q05940 2/20 0.39
PDCD1 Q15116 1/20 0.39
CD274 Q9NZQ7 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL7894663 0.85 MEN1 (0.48) MEN1KMT2ACHRNB4CHRNA3HRH3
SCHEMBL1132942 0.78
SCHEMBL158812 0.78
Ammonia Solution, Strong SCHEMBL1327720 0.76
SCHEMBL11466316 0.73 MC4R (0.46)
SCHEMBL8565864 0.73 MC4R (0.46)
SCHEMBL16765733 0.72
Succinic Acid SCHEMBL29509251 0.70 POLB (0.50) MEN1KMT2A
SCHEMBL8663405 0.70 POLB (0.44) MEN1KMT2A
SCHEMBL6645372 0.69 FFAR1 (0.52) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018162986-A2 NITRODIARYLETHENES AS FLUORESCENCE QUENCHERS FOR NUCLEIC ACID PROBES ELITECHGROUP B.V. (NL) 2018-09-13 WO disclosed