Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 2/20 | 0.46 |
| ▸ | MC3R | P41968 | 2/20 | 0.46 |
| ▸ | MC1R | Q01726 | 2/20 | 0.46 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CCR3 | P51677 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11466316 | 1.00 | MC4R (0.46) | MC4RMC3RMC1RSCD5GABRA1 | |
| SCHEMBL350911 | 0.95 | HSD11B1 (0.48) | SLC18A3 | |
| SCHEMBL3764570 | 0.78 | HTR6 (0.54) | — | |
| SCHEMBL5152847 | 0.78 | MC4R (0.49) | MC4RMC3RMC1RSCD5GABRA1 | |
| SCHEMBL16488227 | 0.78 | HTR6 (0.54) | — | |
| SCHEMBL23459127 | 0.77 | SCD5 (0.57) | MC4RMC3RMC1RSCD5GABRA1 | |
| SCHEMBL908981 | 0.77 | SCD5 (0.57) | MC4RMC3RMC1RSCD5GABRA1 | |
| SCHEMBL2997593 | 0.76 | — | — | |
| SCHEMBL5530480 | 0.76 | — | — | |
| Biphenyl SCHEMBL7894663 | 0.76 | MEN1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0880501-A1 | HETEROCYCLIC COMPOUNDS USEFUL AS PHARMACEUTICAL AGENTS | ZENECA LIMITED (GB) | 1998-12-02 | — | — | EP | disclosed |
| WO-1997028128-A1 | HETEROCYCLIC COMPOUNDS USEFUL AS PHARMACEUTICAL AGENTS | ZENECA LIMITED (GB) | 1997-08-07 | — | — | WO | disclosed |