Trolox

Trolox

SCHEMBL7895023

COC.Cc1c(C)c2c(c(C)c1O)CCC(C)(C(=O)O)O2

nearest known ligand 0.91

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.91
PTGS2 P35354 1/20 0.91
CYP1A2 P05177 1/20 0.91
CYP3A4 P08684 1/20 0.91
TSHR P16473 1/20 0.91
PSEN1 P49768 5/20 0.56
ALOX5 P09917 3/20 0.46
NR1I2 O75469 1/20 0.46
BCHE P06276 7/20 0.45
ACHE P22303 7/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trolox SCHEMBL1927837 0.96 PTGS1 (1.00) PTGS1PTGS2CYP1A2CYP3A4TSHR
Trolox SCHEMBL4647438 0.96 PTGS1 (1.00) PTGS1PTGS2CYP1A2CYP3A4TSHR
Trolox SCHEMBL29375939 0.96 PTGS1 (1.00) PTGS1PTGS2CYP1A2CYP3A4TSHR
Trolox SCHEMBL29653919 0.96 PTGS1 (1.00) PTGS1PTGS2CYP1A2CYP3A4TSHR
(R)-Trolox SCHEMBL615168 0.96 PTGS1 (1.00) PTGS1PTGS2CYP1A2CYP3A4TSHR
Trolox SCHEMBL3226 0.96 PTGS1 (1.00) PTGS1PTGS2CYP1A2CYP3A4TSHR
Trolox SCHEMBL1651402 0.96 PTGS1 (1.00) PTGS1PTGS2CYP1A2CYP3A4TSHR
Trolox SCHEMBL17713594 0.90 PTGS1 (0.89) PTGS1PTGS2CYP1A2CYP3A4TSHR
Trolox SCHEMBL8523345 0.89 PTGS1 (0.86) PTGS1PTGS2CYP1A2CYP3A4TSHR
Trolox SCHEMBL20746198 0.88 PTGS1 (0.84) PTGS1PTGS2CYP1A2CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107365709-A The bioactivity fraction and its preparation and application of photosynthetic organism from stress-induced ISP 投资有限责任公司 2017-11-21 CN disclosed
CN-103096872-B Cosmetic compositions comprising fig serum fraction and methods for reducing the appearance of skin hyperpigmentation 宝洁公司 2017-01-18 CN disclosed
CN-103200929-A Bioactive compositions comprising ficus serum fraction and methods to reduce the appearance of skin hyperpigmentation AKZO NOBEL CHEMICALS INT BV 2013-07-10 CN disclosed
CN-102725395-A Bioactive fractions from stress-induced photosynthetic organisms and methods of making and using same INTEGRATED BOTAN TECHNOLOGIES LLC 2012-10-10 CN disclosed
US-6313247-B1 Cinchonan based chiral selectors for separation of stereoisomers LINDNER WOLFGANG (AT) 2001-11-06 US disclosed
US-5516944-A ENANTIOMORPHS WITH PHOSPHINE GROUPS FOR FORMING METAL COMPLEXES HOFFMANN-LA ROCHE INC. (US) 1996-05-14 US disclosed