Trolox

Trolox

SCHEMBL4647438

Cc1c(C)c2c(c(C)c1O)CCC(C)(C(=O)O)O2.Cc1c(C)c2c(c(C)c1O)CCC(C)(C(=O)O)O2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 1.00
PTGS2 P35354 1/20 1.00
CYP1A2 P05177 1/20 1.00
CYP3A4 P08684 1/20 1.00
TSHR P16473 1/20 1.00
PSEN1 P49768 4/20 0.56
ALOX5 P09917 3/20 0.49
NR1I2 O75469 1/20 0.49
BCHE P06276 5/20 0.47
ACHE P22303 5/20 0.47
CAPN1 P07384 1/20 0.45
MAPT P10636 2/20 0.45
LMNA P02545 2/20 0.45
MEN1 O00255 1/20 0.45
GSTP1 P09211 1/20 0.45
TTPA P49638 1/20 0.45
KMT2A Q03164 1/20 0.45
USP2 O75604 1/20 0.45
THRB P10828 1/20 0.45
CYP2C9 P11712 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trolox SCHEMBL1927837 1.00 PTGS1 (1.00) PTGS1PTGS2CYP1A2CYP3A4TSHR
Trolox SCHEMBL3226 1.00 PTGS1 (1.00) PTGS1PTGS2CYP1A2CYP3A4TSHR
(R)-Trolox SCHEMBL615168 1.00 PTGS1 (1.00) PTGS1PTGS2CYP1A2CYP3A4TSHR
Trolox SCHEMBL29375939 1.00 PTGS1 (1.00) PTGS1PTGS2CYP1A2CYP3A4TSHR
Trolox SCHEMBL29653919 1.00 PTGS1 (1.00) PTGS1PTGS2CYP1A2CYP3A4TSHR
Trolox SCHEMBL1651402 1.00 PTGS1 (1.00) PTGS1PTGS2CYP1A2CYP3A4TSHR
Trolox SCHEMBL7895023 0.96 PTGS1 (0.91) PTGS1PTGS2CYP1A2CYP3A4TSHR
Trolox SCHEMBL17713594 0.94 PTGS1 (0.89) PTGS1PTGS2CYP1A2CYP3A4TSHR
Trolox SCHEMBL8523345 0.93 PTGS1 (0.86) PTGS1PTGS2CYP1A2CYP3A4TSHR
Trolox SCHEMBL20746198 0.92 PTGS1 (0.84) PTGS1PTGS2CYP1A2CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116444610-A Milk active peptide DASAQUR and preparation method and application thereof 内蒙古伊利实业集团股份有限公司 2023-07-18 CN disclosed
EP-3233819-A1 METHODS FOR CHIRAL RESOLUTION OF TROLOX BIOELECTRON TECHNOLOGY CORPORATION (US) 2017-10-25 EP disclosed
US-20170008978-A1 Family of Pain Producing Substances and Methods to Produce Novel Analgesic Drugs UNIV TEXAS (US) 2017-01-12 US disclosed
WO-2016100576-A9 METHODS FOR CHIRAL RESOLUTION OF TROLOX EDISON PHARMACEUTICALS, INC. (US) 2016-11-10 WO disclosed
WO-2016100576-A1 METHODS FOR CHIRAL RESOLUTION OF TROLOX EDISON PHARMACEUTICALS, INC. (US) 2016-06-23 WO disclosed
EP-1956901-A2 PESTICIDALLY ACTIVE COMPOSITIONS HAVING ENHANCED ACTIVITY Dow AgroSciences LLC (US) 2008-08-20 EP disclosed
WO-2007053760-A2 PESTICIDALLY ACTIVE COMPOSITIONS HAVING ENHANCED ACTIVITY DOW AGROSCIENCES LLC (US) 2007-05-10 WO disclosed
US-20070104750-A1 Pesticidally active compositions having enhanced activity DOW AGROSCIENCES LLC (US) 2007-05-10 US disclosed
EP-1781113-A1 A PROCESS OF PRODUCING ROOIBOS TEA EXTRACT The University of Stellenbosch (ZA) 2007-05-09 EP disclosed
WO-2006013530-A1 A PROCESS OF PRODUCING ROOIBOS TEA EXTRACT THE UNIVERSITY OF STELLENBOSCH (ZA) 2006-02-09 WO disclosed
US-20040086420-A1 Methods for sterilizing serum or plasma CLEARANT, INC. 2004-05-06 US disclosed
US-5080886-A 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid and superoxide dismutase STERLING DRUG INC. (US) 1992-01-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170008978-A1 Family of Pain Producing Substances and Methods to Produce Novel Analgesic Drugs ALOX15B, ALOX5, ALOX15 PTGS1 14/4885PTGS2 15/4885CYP1A2 145/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.