Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CES2 | O00748 | 2/20 | 0.50 |
| ▸ | CES1 | P23141 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6522079 | 0.85 | TDP1 (0.57) | TDP1ALDH1A1LMNACES2CES1 | |
| SCHEMBL418469 | 0.85 | TDP1 (0.57) | TDP1ALDH1A1LMNACES2CES1 | |
| SCHEMBL20942796 | 0.82 | CYP3A4 (0.52) | TDP1ALDH1A1LMNACES2CES1 | |
| SCHEMBL777317 | 0.82 | TDP1 (0.53) | TDP1ALDH1A1LMNACES2CES1 | |
| SCHEMBL779855 | 0.82 | TDP1 (0.53) | TDP1ALDH1A1LMNACES2CES1 | |
| SCHEMBL419273 | 0.79 | TDP1 (0.55) | TDP1ALDH1A1LMNACES2CES1 | |
| SCHEMBL10567851 | 0.78 | TPMT (0.48) | TDP1ALDH1A1NPC1RAB9AATM | |
| SCHEMBL28678887 | 0.77 | CYP3A4 (0.50) | TDP1ALDH1A1LMNACES2CES1 | |
| SCHEMBL28367199 | 0.77 | KMT2A (0.51) | TDP1ALDH1A1LMNACES2CES1 | |
| SCHEMBL4939890 | 0.77 | LMNA (0.58) | TDP1ALDH1A1LMNACES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113929798-B | Solid catalyst component and catalyst system for olefin polymerization | 中国石油化工股份有限公司 | 2023-07-21 | — | — | CN | disclosed |
| US-6190847-B1 | INTENDED TO CREATE IMAGES FOR SCANNING. | EASTMAN KODAK COMPANY | 2001-02-20 | — | — | US | disclosed |
| EP-0038988-B1 | ORGANIC PEROXIDE COMPOSITIONS | Interox Chemicals Limited (GB) | 1984-07-04 | — | — | EP | disclosed |
| US-4376218-A | CONTAINING BOTH LIQUID AND SOLID PLASTICIZERS | INTEROX CHEMICALS LIMITED (GB) | 1983-03-08 | — | — | US | disclosed |
| EP-0038988-A1 | Organic peroxide compositions | Interox Chemicals Limited (GB) | 1981-11-04 | — | — | EP | disclosed |