SCHEMBL28367199

SCHEMBL28367199

Cc1ccc(C(=O)OP(=O)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.51
MEN1 O00255 2/20 0.51
RAB9A P51151 6/20 0.49
NPC1 O15118 5/20 0.49
TDP1 Q9NUW8 2/20 0.48
CES2 O00748 1/20 0.48
CES1 P23141 1/20 0.48
SMN1; SMN2 Q16637 4/20 0.46
MAPT P10636 2/20 0.46
AKR1C3 P42330 1/20 0.46
LMNA P02545 2/20 0.46
POLB P06746 1/20 0.45
ALDH1A1 P00352 3/20 0.44
PTGS2 P35354 1/20 0.44
PTK2B Q14289 1/20 0.42
RXFP1 Q9HBX9 1/20 0.42
ESR1 P03372 1/20 0.42
ESR2 Q92731 1/20 0.42
GAA P10253 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1604197 0.87 LMNA (0.52) KMT2AMEN1RAB9ANPC1TDP1
SCHEMBL28366879 0.83 MEN1 (0.53) KMT2AMEN1RAB9ANPC1TDP1
SCHEMBL28366729 0.83 CES2 (0.54) KMT2AMEN1RAB9ANPC1CES2
SCHEMBL28366812 0.82 ALDH1A1 (0.46) KMT2AMEN1RAB9ANPC1TDP1
SCHEMBL28366726 0.82 L3MBTL1 (0.54) KMT2AMEN1RAB9ANPC1TDP1
SCHEMBL28366876 0.80 KMT2A (0.49) KMT2AMEN1RAB9ANPC1TDP1
SCHEMBL28884169 0.79 MEN1 (0.44) KMT2AMEN1RAB9ANPC1SMN1; SMN2
SCHEMBL7895149 0.77 TDP1 (0.59) KMT2AMEN1RAB9ANPC1TDP1
SCHEMBL30292582 0.77 NPC1 (0.47) KMT2AMEN1RAB9ANPC1SMN1; SMN2
SCHEMBL890976 0.77 ALDH1A1 (0.40) KMT2AMEN1SMN1; SMN2LMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110903419-B Solid catalyst component for olefin polymerization, catalyst and application thereof 中国石油化工股份有限公司 2021-07-30 CN disclosed
CN-110903420-B Solid catalyst component for olefin polymerization, catalyst and application thereof 中国石油化工股份有限公司 2021-07-30 CN disclosed
CN-110903418-B Solid catalyst component for olefin polymerization, catalyst and application thereof 中国石油化工股份有限公司 2021-07-02 CN disclosed
CN-110903417-B Solid catalyst component for olefin polymerization, catalyst and application thereof 中国石油化工股份有限公司 2021-07-02 CN disclosed
CN-110903418-A Solid catalyst component for olefin polymerization, catalyst and application thereof 中国石油化工股份有限公司 2020-03-24 CN disclosed
CN-110903417-A Solid catalyst component for olefin polymerization, catalyst and application thereof 中国石油化工股份有限公司 2020-03-24 CN disclosed
CN-110903419-A Solid catalyst component for olefin polymerization, catalyst and application thereof 中国石油化工股份有限公司 2020-03-24 CN disclosed
CN-110903420-A Solid catalyst component for olefin polymerization, catalyst and application thereof 中国石油化工股份有限公司 2020-03-24 CN disclosed