Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.53 |
| ▸ | HCAR3 | P49019 | 10/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CASP6 | P55212 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5098503 | 0.89 | CASP6 (0.62) | APEX1HCAR3TSHRCASP6LMNA | |
| SCHEMBL3866808 | 0.88 | APEX1 (0.66) | APEX1HCAR3TSHRCASP6ALDH1A1 | |
| SCHEMBL6450193 | 0.82 | VCAM1 (0.59) | APEX1HCAR3TSHRCASP6ALDH1A1 | |
| SCHEMBL11680786 | 0.76 | CASP6 (0.64) | APEX1HCAR3TSHRCASP6ALDH1A1 | |
| SCHEMBL1025382 | 0.76 | APEX1 (0.69) | APEX1HCAR3TSHRCASP6ALDH1A1 | |
| SCHEMBL9731903 | 0.75 | MAPT (0.50) | APEX1TSHRCASP6ALDH1A1LMNA | |
| SCHEMBL20857019 | 0.75 | PARP1 (0.59) | APEX1ALDH1A1LMNAMAPTPOLB | |
| SCHEMBL16955575 | 0.74 | MAPT (0.56) | APEX1TSHRCASP6ALDH1A1LMNA | |
| SCHEMBL1025384 | 0.73 | APEX1 (0.66) | APEX1HCAR3TSHRCASP6ALDH1A1 | |
| SCHEMBL856086 | 0.73 | APEX1 (0.66) | APEX1HCAR3TSHRCASP6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187804-B1 | Antibiotic compounds | ZENECA LIMITED (GB) | 2001-02-13 | — | — | US | disclosed |