Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 8/20 | 0.52 |
| ▸ | PIK3CG | P48736 | 6/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 4/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | PRKDC | P78527 | 1/20 | 0.37 |
| ▸ | ATR | Q13535 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL796868 | 0.84 | PIK3CG (0.60) | PI4KAPIK3CGPIK3CDPIK3CA | |
| SCHEMBL10277282 | 0.83 | PIK3CG (0.48) | PI4KAPIK3CGKCNH2PIK3CDPIK3CA | |
| SCHEMBL791172 | 0.83 | PI4KA (0.68) | PI4KAPIK3CGPIK3CDPIK3CAMTOR | |
| SCHEMBL806962 | 0.82 | PI4KA (0.62) | PI4KAPIK3CGPIK3CDPIK3CAMTOR | |
| SCHEMBL807197 | 0.81 | PIK3CG (0.59) | PI4KAPIK3CGPIK3CDPIK3CAMTOR | |
| SCHEMBL790922 | 0.81 | PI4KA (0.60) | PI4KAPIK3CGPIK3CDPIK3CAMTOR | |
| SCHEMBL10274684 | 0.81 | PIK3CG (0.60) | PI4KAPIK3CGPIK3CDPIK3CAMTOR | |
| SCHEMBL790314 | 0.81 | PIK3CG (0.56) | PI4KAPIK3CGPIK3CDPIK3CA | |
| SCHEMBL790025 | 0.81 | PIK3CG (0.56) | PI4KAPIK3CGPIK3CDPIK3CAMTOR | |
| SCHEMBL789858 | 0.80 | PI4KA (0.59) | PI4KAPIK3CGPIK3CDPIK3CAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |