Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 1/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | BCL2 | P10415 | 1/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CXCR3 | P49682 | 4/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3479828 | 0.82 | MAPK9 (0.52) | MAPK9MAPK10KMT2AMEN1BCL2 | |
| SCHEMBL3479929 | 0.81 | DRD2 (0.60) | MAPK9MAPK10KMT2AMEN1BCL2 | |
| SCHEMBL6431934 | 0.80 | MAPK9 (0.47) | MAPK9MAPK10KMT2AMEN1BCL2 | |
| SCHEMBL2425191 | 0.80 | MAPK9 (0.51) | MAPK9MAPK10KMT2AMEN1BCL2 | |
| SCHEMBL3479858 | 0.78 | MAPK9 (0.47) | MAPK9MAPK10KMT2AMEN1BCL2 | |
| SCHEMBL2427324 | 0.78 | P2RY12 (0.51) | MAPK9MAPK10KMT2AMEN1 | |
| SCHEMBL7894679 | 0.78 | MAPK9 (0.54) | MAPK9MAPK10KMT2AMEN1BCL2 | |
| SCHEMBL3480052 | 0.78 | MAPK9 (0.51) | MAPK9MAPK10KMT2AMEN1MAPT | |
| SCHEMBL2423054 | 0.78 | MAPK9 (0.59) | MAPK9MAPK10KMT2AMEN1BCL2 | |
| SCHEMBL2421148 | 0.77 | MAPK9 (0.57) | MAPK9MAPK10KMT2AMEN1BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1088821-A1 | Pharmaceutically active sulfonamide derivatives | Applied Research Systems ARS Holding N.V. (AN) | 2001-04-04 | — | — | EP | claimed |
| EP-1088821-A1 | Pharmaceutically active sulfonamide derivatives | Applied Research Systems ARS Holding N.V. (AN) | 2001-04-04 | — | — | EP | disclosed |