Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 3/20 | 0.59 |
| ▸ | XBP1 | P17861 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7893043 | 0.92 | KMT2A (0.73) | MAPTMEN1KMT2ARAB9AALOX15 | |
| SCHEMBL7890537 | 0.89 | RXFP1 (0.70) | MAPTMEN1KMT2ARAB9AALOX15 | |
| SCHEMBL7885305 | 0.84 | KMT2A (0.59) | MAPTMEN1KMT2ARAB9AALOX15 | |
| SCHEMBL7894969 | 0.83 | TSHR (0.66) | MAPTMEN1KMT2ARAB9ATSHR | |
| SCHEMBL7892443 | 0.82 | TSHR (0.67) | MAPTMEN1KMT2ARAB9AALOX15 | |
| SCHEMBL7894813 | 0.79 | MEN1 (0.52) | MAPTMEN1KMT2ARAB9AALOX15 | |
| SCHEMBL7885318 | 0.77 | TSHR (0.76) | MEN1KMT2AALOX15TSHRCYP1A2 | |
| SCHEMBL13799881 | 0.76 | ALOX15 (1.00) | MAPTMEN1KMT2ARAB9AALOX15 | |
| SCHEMBL31703144 | 0.76 | ALOX15 (1.00) | MAPTMEN1KMT2ARAB9AALOX15 | |
| Hydrochloric Acid SCHEMBL28917129 | 0.76 | ENPP1 (0.58) | MAPTMEN1KMT2ARAB9AALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6180629-B1 | INDUCING OR PROMOTING APOPTOSIS AND FOR ARRESTING UNCONTROLLED NEOPLASTIC CELL PROLIFERATION, INCLUDING PRECANCEROUS AND CANCEROUS LESIONS | CELL PATHWAYS, INC. | 2001-01-30 | — | — | US | disclosed |